Condition

Invasive Breast Cancer clinical trials and research

• 13Clinical trials
• 5NIH research projects
• 1New in 30 days
• 4Countries

Newest Invasive Breast Cancer clinical trials

All recruiting trials (13)

• 68Ga-FAPI PET/MRI imaging to see if it can track breast cancer response to chemotherapy

  This study tests whether a new imaging scan, 68Ga-FAPI PET/MRI, can show how well invasive breast cancer responds to neoadjuvant chemotherapy in adults.

  Recruiting at 8 sites Phase 1 Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 7 other locations · NCT07899892

• Making organoids from breast tumors before and after neoadjuvant chemotherapy

  This project will test whether lab-grown mini-tumors (patient-derived organoids) and blood biomarkers can help predict who will have a complete response to neoadjuvant chemotherapy for invasive breast cancer.

  Recruiting Istituti Clinici Scientifici Maugeri SpA · Pavia, PV · NCT07260188

• Comparing concurrent and sequential chemotherapy with radiation for breast cancer

  This study is testing whether getting chemotherapy and radiation at the same time works better than getting them one after the other for people with stage IIB-III breast cancer.

  Recruiting Phase 3 Tata Memorial Centre · Vishkhapatnam, Andhra Pradesh and 4 other locations · NCT06926543

• Preoperative partial breast irradiation for early-stage breast cancer

  This study is testing if giving radiation therapy before surgery for early-stage breast cancer can lead to fewer side effects compared to the usual treatment given after surgery.

  Recruiting Phase 2 Yonsei University · Seoul · NCT06677944

• Using MRI to detect early breast cancer metastases

  This study is testing if a special type of MRI can help find early signs of breast cancer returning in high-risk patients to see if it can improve their chances of living longer.

  Recruiting European Institute of Oncology · Milan · NCT06328465

• Using tart cherry juice to prevent nerve damage from chemotherapy in breast cancer patients

  This study is testing if drinking tart cherry juice can help prevent nerve damage in breast cancer patients receiving chemotherapy.

  Recruiting Phase 2 University of California, Davis · Sacramento, California · NCT06268665

• Testing a new drug combination for HER2-positive inflammatory breast cancer

  This study is testing a new combination of two drugs to see if they can safely and effectively treat people with stage III HER2-positive inflammatory breast cancer who haven't had treatment before.

  Recruiting at 3 sites Phase 2 Dana-Farber Cancer Institute · Boston, Massachusetts and 2 other locations · NCT05795101

• Alternative treatment for T4 breast cancer involving preoperative radiotherapy and immediate reconstruction

  This study is testing a new treatment for T4 breast cancer that combines radiation before surgery with immediate reconstruction to see if it can improve patient outcomes.

  Recruiting at 7 sites Phase 1 Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 6 other locations · NCT05412225

• Vitamin D supplementation for patients with triple negative breast cancer

  This study is testing if giving vitamin D to patients with triple negative breast cancer who are low in vitamin D can help them respond better to chemotherapy compared to those who have enough vitamin D.

  Recruiting Phase 2 Wake Forest University Health Sciences · Winston-Salem, North Carolina · NCT04677816

• Treatment for early-stage HER2 low, hormone receptor positive breast cancer

  This study is testing whether a new treatment combining trastuzumab deruxtecan and anastrozole can help people with early-stage HER2 low, hormone receptor positive breast cancer do better than just using trastuzumab deruxtecan alone.

  Recruiting at 7 sites Phase 2 Jonsson Comprehensive Cancer Center · Fullerton, California and 8 other locations · NCT04553770

• Using MRI-guided radiation therapy for treating certain cancers

  This study is testing if using MRI to guide radiation therapy along with chemotherapy can safely and effectively treat patients with gastric and breast cancers.

  Recruiting at 2 sites Brigham and Women's Hospital · Boston, Massachusetts and 1 other locations · NCT04368702

• Evaluating sacituzumab govitecan for localized triple negative breast cancer

  This study is testing a new drug called sacituzumab govitecan for people with localized triple negative breast cancer to see if it can help them.

  Recruiting at 4 sites Phase 2 Massachusetts General Hospital · Boston, Massachusetts and 4 other locations · NCT04230109

• Collection of breast cancer tissue and blood samples

  This study is collecting breast cancer tissue and blood samples from patients during surgery to help with future research on the disease.

  Recruiting Thomas Jefferson University · Philadelphia, Pennsylvania · NCT04074720

NIH-funded research (5)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Understanding why DCIS becomes invasive breast cancer in Asian American and Native Hawaiian/Pacific Islander groups

  A research project aims to identify biological factors and risk patterns that predict when early-stage DCIS may progress to invasive breast cancer, with a focus on AANHPI populations.

  NIH research University of Hawaii at Manoa · Honolulu, United States · NIH-11449258

• Imaging test to show whether non-invasive breast tumor treatment has worked

  This project is creating a non-contrast MRI tool powered by AI to quickly show if focused ultrasound has destroyed a localized breast tumor for people with early-stage breast cancer.

  NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11251261

• A new imaging method to assess tissue health during breast cancer treatment

  This study is testing a new way to check how well breast cancer treatments are working by using special MRI scans that don’t require any injections, helping doctors see if the tumor is responding to treatment and making sure patients get the best care possible.

  NIH research University of Utah · Salt Lake City, United States · NIH-11009526

• Using advanced MRI techniques to improve breast cancer treatment.

  This study is working on improving breast cancer treatment by using new MRI techniques that combine advanced technology and machine learning, so patients can get clearer images of how well their treatments are working, leading to better care and outcomes.

  NIH research University of Utah · Salt Lake City, United States · NIH-10997959

• Investigating how a specific protein contributes to the progression of breast cancer

  This study is looking at a protein called cyclin E and how its changes might lead to aggressive breast cancer, with the hope that understanding these early changes can help improve early detection and treatment options for patients.

  NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-10550153

Related topics

Quick answers

How many Invasive Breast Cancer clinical trials are recruiting right now?

13, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in United States (9 trials), Italy (2 trials), India (1 trial), South Korea (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 6, Phase 1: 2, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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