Condition

Breast Cancer Stage III clinical trials and research

• 16Clinical trials
• 5Countries

Newest Breast Cancer Stage III clinical trials

All recruiting trials (16)

• Capecitabine for MRD-positive, resected ER+/HER2-negative breast cancer

  This Phase 2 trial tests whether taking capecitabine can help people with resected, ER-positive/HER2-negative breast cancer who still have molecular residual disease after standard therapy.

  Recruiting Phase 2 University Health Network, Toronto · Toronto, Ontario · NCT07631052

• Biobran (rice bran arabinoxylan) supplement to support breast cancer chemotherapy

  This will test whether taking 3 grams daily of Biobran for 24 weeks helps women with stage I–III breast cancer tolerate paclitaxel and doxorubicin chemotherapy and have fewer side effects.

  Recruiting China Medical University Hospital · Taichung and 1 other locations · NCT07503496

• Meaning-Centered Therapy for Latinos for adults with advanced cancer

  This study tests whether Meaning-Centered Psychotherapy for Latinos (MCP-L) can reduce anxiety and depression and improve quality of life compared with CBT in Spanish-speaking adults with advanced cancer.

  Recruiting Memorial Sloan Kettering Cancer Center · New York, New York and 1 other locations · NCT07225309

• SBRT with intratumoural pembrolizumab before neoadjuvant chemotherapy for high-risk breast cancer

  This study will test whether a short course of focused radiation plus two injections of pembrolizumab into the tumor before chemotherapy helps people with high‑risk invasive breast cancer respond better to treatment.

  Recruiting Phase 2 London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · London, Ontario and 1 other locations · NCT07188246

• Predicting how hormone therapy before surgery affects breast cancer

  This study is testing how hormone therapy before surgery can help people with early-stage breast cancer and what it means for their tumors.

  Recruiting Phase 2 George Washington University · Washington D.C., District of Columbia · NCT06806930

• Meal timing during cancer treatment for Alaska Native and American Indian patients

  This test will see if an 8-hour time-restricted eating schedule during neoadjuvant or adjuvant therapy helps Alaska Native and American Indian adults with rectal or certain breast cancers.

  Recruiting Fred Hutchinson Cancer Center · Anchorage, Alaska · NCT06802172

• Memantine plus structured exercise to protect thinking and memory during breast cancer chemotherapy

  This will test whether memantine combined with a supervised exercise program, memantine alone, or a placebo can prevent or reduce thinking and memory problems in people receiving chemotherapy for stage I–III breast cancer.

  Recruiting Phase 2 UNC Lineberger Comprehensive Cancer Center · Chapel Hill, North Carolina · NCT06727773

• Language interpretation solutions for breast cancer patients

  This study is testing different ways to help Spanish- and Mandarin-speaking breast cancer patients communicate better with their doctors during appointments.

  Recruiting at 8 sites Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 7 other locations · NCT06721065

• Improving surgical decisions for young women with breast cancer

  This study is testing a new online tool to help young women with breast cancer make better surgical decisions and communicate more effectively with their doctors.

  Recruiting at 4 sites Weill Medical College of Cornell University · New Haven, Connecticut and 3 other locations · NCT06275126

• Using tart cherry juice to prevent nerve damage from chemotherapy in breast cancer patients

  This study is testing if drinking tart cherry juice can help prevent nerve damage in breast cancer patients receiving chemotherapy.

  Recruiting Phase 2 University of California, Davis · Sacramento, California · NCT06268665

• Evaluating skin reactions in breast cancer patients receiving proton therapy

  This study is testing a new technique to see if it can help reduce skin reactions in breast cancer patients getting proton therapy.

  Recruiting Covenant Health Cancer Center · Knoxville, Tennessee · NCT06006806

• Virtual rehabilitation program for cancer survivors

  This study is testing an 8-week online rehab program for cancer survivors to see if it helps them feel better physically and socially after treatment.

  Recruiting University Health Network, Toronto · Toronto, Ontario · NCT05898789

• Radiation therapy tailored to tumor biology for advanced breast cancer

  This study is testing if adjusting radiation therapy based on how well tumors respond to earlier chemotherapy can help people with advanced breast cancer live longer and feel better after treatment.

  Recruiting Samsung Medical Center · Seoul · NCT05896865

• Evaluating immune and clinical responses in early-stage triple negative breast cancer with chemo-immunotherapy

  This study is testing if a combination of chemotherapy and immunotherapy can help people with early-stage triple negative breast cancer by looking at their immune responses and how well the treatment works.

  Recruiting Emory University · Atlanta, Georgia · NCT05877859

• Combining chemotherapy and radiation for high-risk breast cancer patients

  This study tests whether combining chemotherapy and radiation can help high-risk breast cancer patients who still have cancer after initial treatment, while also looking at how this treatment affects their immune system.

  Recruiting Phase 2/3 University of Virginia · Charlottesville, Virginia · NCT05288777

• Understanding how tumor shrinkage predicts cancer response in early breast cancer patients

  This study tests if measuring how much breast tumors shrink during chemotherapy can help predict how well the treatment will work for women with early-stage breast cancer.

  Recruiting at 2 sites Phase 2 Baylor Breast Care Center · Houston, Texas and 1 other locations · NCT05020860

Related topics

Quick answers

How many Breast Cancer Stage III clinical trials are recruiting right now?

16, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (11 trials), Canada (3 trials), South Korea (1 trial), Taiwan (1 trial), Mexico (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 6, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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