Condition

Breast Cancer Invasive clinical trials and research

• 21Clinical trials
• 12Countries

Newest Breast Cancer Invasive clinical trials

All recruiting trials (21)

• ATUSA 3D automated breast ultrasound for suspicious breast lesions

  This study will test whether the ATUSA 3D automated breast ultrasound system can produce high-quality images that match biopsy results in women with BI-RADS 4 or 5 breast findings.

  Recruiting at 2 sites iSono Health, Inc. · Sacramento, California and 1 other locations · NCT07505797

• SBRT with intratumoural pembrolizumab before neoadjuvant chemotherapy for high-risk breast cancer

  This study will test whether a short course of focused radiation plus two injections of pembrolizumab into the tumor before chemotherapy helps people with high‑risk invasive breast cancer respond better to treatment.

  Recruiting Phase 2 London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · London, Ontario and 1 other locations · NCT07188246

• Detecting cancer margins during breast surgery using advanced imaging technology

  This study is testing a new imaging system that helps surgeons find cancerous tissue more accurately during breast cancer surgery to improve patient outcomes.

  Recruiting University of Nottingham · Nottingham · NCT06977698

• Confocal Histolog Scanner for checking margins during lumpectomy

  This project will test whether using a confocal Histolog Scanner during lumpectomy helps surgeons find cancer at the edges of removed tissue and reduce the need for repeat operations in women having breast-conserving surgery.

  Recruiting University of Fribourg · Villars-sûr-glâne, Canton of Fribourg · NCT06958991

• Evaluating Circulating Tumor Cells in Breast Cancer Follow-up

  This study is testing a new way to track cancer cells in the blood of breast cancer patients to see how their condition changes during treatment.

  Recruiting ScreenCell · Neuilly-sur-Seine · NCT06807502

• Using 68Ga-FAPi-46 PET/CT to study breast cancer

  This study is testing a new imaging method using a special agent to see if it can help women with node-positive breast cancer get better information about their tumors before starting treatment.

  Recruiting European Institute of Oncology · Milan, Italy · NCT06790264

• Combining Serplulimab with Chemotherapy for Early-stage HR+/HER2- Breast Cancer

  This study is testing if adding a new drug called serplulimab to standard chemotherapy helps people with early-stage HR+/HER2- breast cancer have better outcomes before surgery.

  Recruiting Henan Cancer Hospital · Zhengzhou · NCT06781281

• Using PET/CT to assess breast cancer treatment effectiveness

  This study is testing a new imaging method to see how well neoadjuvant therapy works for patients with invasive breast cancer.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai · NCT06725940

• Comparing endoscopic-assisted and conventional breast-conserving surgery for breast cancer patients

  This study is testing whether a new type of breast surgery called endoscopic-assisted surgery works better than the traditional method for women with breast cancer who have already received treatment.

  Recruiting Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong and 1 other locations · NCT06716073

• AI-assisted radiotherapy for breast cancer after surgery

  This study is testing a new AI-assisted radiotherapy method for women with invasive breast cancer after surgery to see if it can make treatment faster and more effective.

  Recruiting Sun Yat-sen University · Guangzhou · NCT06686459

• Using nanopore sequencing for faster breast cancer diagnosis in Tanzania

  This study is testing if a new method called nanopore sequencing can help doctors in Tanzania diagnose breast cancer faster and more accurately than the usual tests.

  Recruiting University of Bonn · Moshi · NCT06633276

• Evaluating outcomes of breast-conserving surgery for cancer patients

  This study is testing how well a specific type of breast surgery works for cancer patients and how it affects their quality of life and recovery, while also considering their personal choices in treatment.

  Recruiting at 3 sites Uppsala University · Sydney and 2 other locations · NCT06401304

• Using tart cherry juice to prevent nerve damage from chemotherapy in breast cancer patients

  This study is testing if drinking tart cherry juice can help prevent nerve damage in breast cancer patients receiving chemotherapy.

  Recruiting Phase 2 University of California, Davis · Sacramento, California · NCT06268665

• Comparing continuous and intermittent use of pyrotinib for HER2-positive breast cancer

  This study is testing whether taking the cancer drug pyrotinib continuously or in intervals helps people with HER2-positive breast cancer do better and feel less side effects after their initial treatment.

  Recruiting Phase 3 RenJi Hospital · Shanghai · NCT05910398

• Evaluating immune and clinical responses in early-stage triple negative breast cancer with chemo-immunotherapy

  This study is testing if a combination of chemotherapy and immunotherapy can help people with early-stage triple negative breast cancer by looking at their immune responses and how well the treatment works.

  Recruiting Emory University · Atlanta, Georgia · NCT05877859

• Omitting breast surgery for certain breast cancer patients after treatment

  This study is testing if certain breast cancer patients who show no signs of cancer after treatment can safely skip surgery and still stay cancer-free for five years.

  Recruiting Seoul National University Hospital · Seoul · NCT05505357

• Educational media for Latinx patients undergoing radiation therapy for breast or prostate cancer

  This study is testing new educational videos and materials to help Spanish-speaking Latinx patients better understand their radiation therapy for breast or prostate cancer and feel more involved in their treatment.

  Recruiting at 2 sites Columbia University · Miami Beach, Florida and 1 other locations · NCT05351424

• Continuing systemic therapy after local treatment for metastatic breast cancer

  This study is testing if continuing treatment after local therapies can help people with metastatic breast cancer feel better and live longer.

  Recruiting at 7 sites Phase 2 The Netherlands Cancer Institute · Alkmaar and 6 other locations · NCT05301881

• Understanding how tumor shrinkage predicts cancer response in early breast cancer patients

  This study tests if measuring how much breast tumors shrink during chemotherapy can help predict how well the treatment will work for women with early-stage breast cancer.

  Recruiting at 2 sites Phase 2 Baylor Breast Care Center · Houston, Texas and 1 other locations · NCT05020860

• Preoperative low dose azacitidine for high-risk early stage breast cancer

  This study is testing if a low dose of azacitidine can boost the immune response in patients with high-risk early stage breast cancer before they have surgery.

  Recruiting Phase 2 University of Illinois Chicago · Chicago, Illinois · NCT04891068

• Using ultrasound imaging to predict breast cancer treatment response

  This study tests if different types of ultrasound imaging can help predict how well breast cancer patients respond to their chemotherapy and radiotherapy treatments.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT00437879

Related topics

Quick answers

How many Breast Cancer Invasive clinical trials are recruiting right now?

21, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 12 countries. The most sites are in United States (6 trials), China (5 trials), United Kingdom (2 trials), Canada (2 trials), South Korea (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 5, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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