Condition

Hypoxic Ischemic Encephalopathy (HIE) clinical trials and research

• 6Clinical trials
• 9Countries

Newest Hypoxic Ischemic Encephalopathy (HIE) clinical trials

All recruiting trials (6)

• Cooling treatment for newborns with hypoxic-ischemic encephalopathy in Vietnam

  This project will test whether cooling (therapeutic hypothermia) helps newborns with hypoxic-ischemic encephalopathy in Vietnam by looking at short-term recovery and long-term brain outcomes.

  Recruiting National Children's Hospital, Vietnam · Ha Nội, Hanoi · NCT07555652

• Two-week intensive brain-focused therapy program for children with neurodevelopmental and chromosomal conditions

  This program will try a two-week, individualized multimodal neurorehabilitation approach for children about 4–12 years old with neurodevelopmental or chromosomal conditions to see if it improves attention, motor skills, communication, and daily functioning.

  Recruiting Healing Hope International · The Woodlands, Texas · NCT07493096

• Preventive dobutamine use in newborns with brain injury from birth as part of cooling

  In babies with hypoxic-ischemic brain injury treated with cooling, this study tests starting dobutamine early to support the heart and potentially protect the brain.

  Recruiting Phase 2 University of Alberta · Edmonton, Alberta and 1 other locations · NCT07406477

• Caffeine for Hypoxic Ischemic Encephalopathy in Newborns

  This trial tests whether giving caffeine to newborns with HIE helps reduce death or severe developmental problems by 18–22 months compared with a placebo.

  Recruiting at 3 sites Phase 3 NICHD Global Network for Women's and Children's Health · Saidpur and 6 other locations · NCT06855108

• Genome sequencing for newborns with perinatal hypoxic‑ischemic encephalopathy

  This program will try genome sequencing for newborns with moderate-to-severe hypoxic‑ischemic encephalopathy who are receiving therapeutic cooling, using parent samples to help interpret results.

  Recruiting at 2 sites Baylor College of Medicine · Houston, Texas and 1 other locations · NCT06762795

• Investigating inflammation and metabolism after cardiac arrest

  This study looks at how inflammation and metabolism change after cardiac arrest to see if they affect recovery and brain health in patients.

  Recruiting MaineHealth · Portland, Maine · NCT02664831

Related topics

Quick answers

How many Hypoxic Ischemic Encephalopathy (HIE) clinical trials are recruiting right now?

6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (3 trials), Canada (1 trial), Bangladesh (1 trial), Democratic Republic of the Congo (1 trial), Guatemala (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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