Condition
Fragile X Syndrome (FXS) clinical trials and research
As of November 12, 2026, Find a Trial lists 5 Fragile X Syndrome (FXS) clinical trials that are recruiting, at sites in 4 countries (most in France (2), United States (1), Italy (1)). By phase: Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 4Countries
Newest Fragile X Syndrome (FXS) clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| CTH120 in Fragile X syndrome: safety and early effectiveness in adult males | Phase 2 | Barcelona, Barcelona and 1 other locations | Recruiting | Jun 17, 2026 |
| Two-week intensive brain-focused therapy program for children with neurodevelopmental and chromosomal conditions | — | The Woodlands, Texas | Recruiting | Mar 25, 2026 |
| Trust in people with intellectual disability: a look at Down syndrome and Fragile X syndrome | — | Bron | Recruiting | Feb 25, 2026 |
| Optical brain imaging for X-linked intellectual disabilities | — | Bron | Recruiting | Mar 11, 2025 |
| Cognitive Behavioral Therapy for Adolescents with Fragile X Syndrome and Autism Spectrum Disorder | — | Rome | Recruiting | Nov 7, 2024 |
All recruiting trials (5)
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CTH120 in Fragile X syndrome: safety and early effectiveness in adult males
This study tests CTH120 versus placebo to see if it is safe and helps adults with Fragile X syndrome.
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Two-week intensive brain-focused therapy program for children with neurodevelopmental and chromosomal conditions
This program will try a two-week, individualized multimodal neurorehabilitation approach for children about 4–12 years old with neurodevelopmental or chromosomal conditions to see if it improves attention, motor skills, communication, and daily functioning.
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Trust in people with intellectual disability: a look at Down syndrome and Fragile X syndrome
This study tests how people with Down syndrome or Fragile X syndrome process trust in social interactions to see how trust decisions differ in these groups.
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Optical brain imaging for X-linked intellectual disabilities
This project will try using noninvasive optical brain imaging (fNIRS) together with cognitive tests in males aged 5–35 who have Fragile X syndrome or creatine transporter deficiency to look for patterns of brain function.
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Cognitive Behavioral Therapy for Adolescents with Fragile X Syndrome and Autism Spectrum Disorder
This study is testing whether cognitive behavioral therapy can help teenagers with Fragile X Syndrome and Autism Spectrum Disorder improve their daily skills and overall quality of life.
Related topics
Quick answers
How many Fragile X Syndrome (FXS) clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 4 countries. The most sites are in France (2 trials), United States (1 trial), Italy (1 trial), Spain (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.