Condition

Hematological Malignancy clinical trials and research

• 15Clinical trials
• 5NIH research projects
• 1New in 30 days
• 9Countries

Newest Hematological Malignancy clinical trials

All recruiting trials (15)

• Middle East study of bloodstream infections in blood cancer patients and HSCT recipients

  This is an observational study to see how bloodstream infections affect adults with blood cancers or after stem cell transplants across several Middle East countries.

  Recruiting at 9 sites Hamad Medical Corporation · Amman and 8 other locations · NCT07900542

• Withaferin A to help prevent graft-versus-host disease after stem cell transplant

  This trial tests whether adding standardized Withaferin A to standard GvHD prevention can help people 18 and older with blood cancers who are getting a matched related donor stem cell transplant.

  Recruiting at 2 sites Phase 1/2 Tata Memorial Centre · Navi Mumbai, Maharashtra and 1 other locations · NCT07724873

• Standardized Withaferin A for steroid-refractory acute GVHD after stem cell transplant

  This study tests whether a standardized extract of Withania somnifera (Withaferin A) given by mouth can help patients with steroid-refractory acute GVHD after an allogeneic stem cell transplant.

  Recruiting Phase 2 Tata Memorial Centre · Navi Mumbai, Maharashtra · NCT07708987

• See if a behavioral coaching plus at-home exercise can help older blood cancer survivors slow aging

  Aimed at people 50 and older who have had a blood cancer, this trial tests whether combining coaching with a virtual exercise program can help slow aging and improve health.

  Recruiting University of Nebraska · Omaha, Nebraska · NCT07292272

• Using Fourth-Generation CAR-T to treat blood cancers

  This study is testing a new type of CAR-T therapy to see if it can safely help people with blood cancers like Multiple Myeloma and B-cell Lymphoma.

  Recruiting Phase 1 The Third Affiliated Hospital of Southern Medical University · Guangzhou, Guangdong · NCT06758713

• Using Thymalfasin and IL-2 to treat low lymphocyte levels in blood cancer patients

  This study is testing if a combination of two injections can help blood cancer patients with low lymphocyte levels feel better and improve their health.

  Recruiting Phase 2 The First Affiliated Hospital of Xiamen University · Xiamen, Fujian · NCT06584006

• Evaluating YY201 in patients with advanced solid tumors and blood cancers

  This study is testing a new treatment called YY201 to see if it can help people with advanced lymphomas and blood cancers who haven't had success with other treatments.

  Recruiting Phase 1 Shanghai Yuyao Biotech Co., Ltd. · Shanghai, Shanghai Municipality · NCT06225856

• Testing OT-A201 for treating blood cancers and solid tumors

  This study is testing a new treatment called OT-A201 to see if it can safely help people with blood cancers and solid tumors that haven't responded to other treatments.

  Recruiting at 4 sites Phase 1 Onward Therapeutics · Montpellier and 3 other locations · NCT05828459

• Collecting long-term safety and survival data from patients treated with Century Therapeutics cellular therapy

  This study is trying to see how safe and effective a cellular therapy is for patients over the long term after they've already received the treatment.

  Recruiting at 4 sites Century Therapeutics, Inc. · Gilbert, Arizona and 6 other locations · NCT05768269

• Using Xerava to prevent infections in patients with blood cancers and low white blood cell counts

  This study is testing if the antibiotic Xerava can help prevent infections in patients with blood cancers who have low white blood cell counts during their treatment.

  Recruiting Phase 2 West Virginia University · Morgantown, West Virginia · NCT05537896

• CXCR4-targeted PET/CT for hematologic cancers

  This study will test whether a CXCR4-targeted PET/CT scan (68Ga‑pentixafor) finds and stages blood-cancer lesions better than the standard 18F‑FDG PET/CT in people with newly diagnosed or relapsed hematological malignancies.

  Recruiting Zhongnan Hospital · Wuhan, Hubei · NCT05255926

• Using engineered NK cells with chemotherapy to treat certain blood cancers

  This study is testing if a new type of immune cell combined with chemotherapy can help people with certain tough-to-treat blood cancers feel better and improve their outcomes.

  Recruiting Phase 1/2 M.D. Anderson Cancer Center · Houston, Texas · NCT05110742

• Investigating DPP4's Role in Treating Leukemia

  This study is testing if a medication that blocks DPP-4 can help prevent relapse in people with acute myeloid leukemia by looking at their blood and bone marrow.

  Recruiting University of Missouri-Columbia · Columbia, Missouri · NCT04841447

• HLA-Haploidentical Stem Cell Transplant with Cyclophosphamide and Bortezomib

  This study is testing a new stem cell transplant method for patients with blood cancers who don't have a matched donor, using special medications to help their bodies accept the transplant and recover better.

  Recruiting Phase 2 Henry Ford Health System · Detroit, Michigan · NCT03850366

• Matching cancer patients with targeted therapies based on their molecular profiles

  This study is testing whether matching cancer patients with targeted treatments based on their unique genetic profiles can improve their chances of getting better.

  Recruiting at 5 sites Institut Bergonié · Bayonne and 6 other locations · NCT02534649

NIH-funded research (5)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Boosting TET Activity to Help Treat AML with Vitamin C

  Vitamin C may help people with a type of blood cancer (AML) by boosting a natural anti-cancer pathway, potentially improving outcomes for adults with this disease.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11398136

• Why people with sickle cell disease have higher risk of blood cancers

  This project is checking if oxidative DNA damage in blood stem cells explains the higher risk of blood cancers after transplants or gene therapy in adults with sickle cell disease.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11310848

• Boosting TET enzymes with vitamin C for acute myeloid leukemia

  This project explores whether giving vitamin C can boost a natural enzyme and help adults with TET2‑mutant acute myeloid leukemia.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11161573

• Understanding why sickle cell disease increases the risk of blood cancers.

  This study is looking at why adults with sickle cell disease might have a higher chance of developing blood cancers, and it aims to find out how stress on their cells and DNA damage could play a role, which could help improve treatments for people with sickle cell disease.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11110191

• Using vitamin C to improve treatment for acute myeloid leukemia

  This study is looking at whether vitamin C can help treat people with acute myeloid leukemia, especially those with a specific gene mutation, by boosting the body's ability to fight cancer and making other treatments work better.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-10895423

Related topics

Quick answers

How many Hematological Malignancy clinical trials are recruiting right now?

15, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (6 trials), China (4 trials), India (2 trials), France (2 trials), Jordan (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 1: 3, Phase 1/2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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