Clinical trial Recruiting at 5 sites Interventional Ages 18 and up

Matching cancer patients with targeted therapies based on their molecular profiles

Official title: Bergonie Institut Profiling : Fighting Cancer by Matching Molecular Alterations and Drugs in Early Phase Trials

Run by Institut Bergonié · NCT02534649 · Data updated 2026-11-12

This study is testing whether matching cancer patients with targeted treatments based on their unique genetic profiles can improve their chances of getting better.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment10000 (estimated)
SponsorInstitut Bergonié
Academic / other
Drugs / interventionsimmunotherapy
Locations7 sites (Bayonne and 6 other locations)
StatusRecruiting
StartedDecember 2015
Main results expectedMarch 2028
Study endsDecember 2029
Registry record updatedOctober 8, 2026
Trial IDNCT02534649 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older with advanced solid tumors or hematological malignancies.

Probably not a fit

Patients who are pregnant, breastfeeding, or have been previously enrolled in this study may not receive any benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to personalize cancer treatment by identifying actionable molecular alterations in patients with advanced solid tumors or hematological malignancies. Using next-generation sequencing and immunological profiling, the study will analyze tumor and blood samples to create a comprehensive molecular profile for each patient. This profile will help clinicians match patients to specific early phase clinical trials that are most likely to benefit them based on their unique genetic characteristics.

Why it matters

Potential benefit: If successful, this approach could lead to more effective and tailored cancer treatments for patients with advanced disease.

How similar studies have gone: Other studies utilizing personalized medicine approaches have shown promise, indicating potential success for this novel methodology.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age ≥ 18 years,
2. Histology: solid malignant tumor or hematological malignancy,
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7. Patient with a social security in compliance with the French law relating to biomedical research (Article L.1121-11 of French Public Health Code),
8. Voluntary signed and dated written informed consent prior to any study specific procedure.

Exclusion Criteria:

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9. Individuals deprived of liberty or placed under guardianship
10. Pregnant or breast feeding women,
11. Previous enrolment in the present study.

Where it's running

  • Centre Hospitalier de la Côte Basque
    Bayonne, France
    Recruiting
  • Clinique Tivoli-Ducos
    Bordeaux, France
    Recruiting
  • Institut Bergonie
    Bordeaux, France
    Recruiting
  • Polyclinique Bordeaux Nord Aquitaine
    Bordeaux, France
    Recruiting
  • Clinique Marzet
    Pau, France
    Recruiting
  • Centre Hospitalier de Pau
    Pau, France
    Not yet recruiting
Show 1 more location
  • Centre Eugène Marquis
    Rennes, France
    Active not recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.