Collecting long-term safety and survival data from patients treated with Century Therapeutics cellular therapy
A Long-Term Follow-up Study for Subjects Previously Treated With A Century Therapeutics Cellular Therapy Product
This study is trying to see how safe and effective a cellular therapy is for patients over the long term after they've already received the treatment.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 375 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Century Therapeutics, Inc. Industry-sponsored |
| Locations | 7 sites (Gilbert, Arizona and 6 other locations) |
| Trial ID | NCT05768269 on ClinicalTrials.gov |
What this trial studies
This observational study aims to gather long-term safety and survival data from participants who have previously been treated with a cellular therapy product in an eligible Century-sponsored index trial. The study focuses on monitoring for any late adverse events and assessing the persistence of the cellular therapy's effects. By collecting this data, researchers hope to identify any long-term risks associated with the treatment and ensure ongoing evaluation of patient safety.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals who have previously participated in a Century-sponsored index trial and received treatment with a cellular therapy product.
Not a fit: Patients who have not received treatment with a cellular therapy product in an eligible index trial will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the long-term safety and effectiveness of cellular therapies for patients with hematological and solid tumor malignancies.
How similar studies have performed: Other studies have successfully collected long-term safety data for cellular therapies, indicating that this approach is supported by previous research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participant has provided written informed consent prior to any long-term follow-up (LTFU) study-specific procedures. * Participants received at least one treatment with a cellular therapy product in an eligible index trial. * Participant was withdrawn, early discontinued or completed an eligible index trial. * Participant is willing and able to comply with scheduled visits, study plan, and other study procedures. Exclusion Criteria: -This study has no exclusion criteria.
Where this trial is running
Gilbert, Arizona and 6 other locations
- Banner MD Anderson Cancer Center — Gilbert, Arizona, United States (Not_yet_recruiting)
- University of Southern California - Norris Comprehensive Cancer Center — Los Angeles, California, United States (Not_yet_recruiting)
- University of Maryland Medical Center — Baltimore, Maryland, United States (Recruiting)
- Corewell Health — Grand Rapids, Michigan, United States (Not_yet_recruiting)
- Levine Cancer Institute — Charlotte, North Carolina, United States (Recruiting)
- University of Cincinnati Medical Center — Cincinnati, Ohio, United States (Recruiting)
- Swedish Cancer Institute — Seattle, Washington, United States (Recruiting)
Study contacts
- Study coordinator: Century Therapeutics Clinical Team
- Email: trial_response_century@centurytx.com
- Phone: 8885067670
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.