Modified Essential Frailty Toolset for older adults having major elective non-cardiac surgery
Official title: Modified Essential Frailty Toolset for Predicting Postoperative Complications and Readmission in Older Adults Undergoing Major Elective Surgery
Run by University of Iceland · NCT07452263 · Data updated 2026-11-12
This project will test whether a quick frailty checklist (the modified Essential Frailty Toolset) can predict complications and hospital readmissions in people aged 70 and older scheduled for major elective non-cardiac surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 70 Years and up |
| Sex | All |
| Enrollment | 250 (estimated) |
| Sponsor | University of Iceland Academic / other |
| Locations | 1 site (Reykjavik, Hofudborgarsvaedid) |
| Status | Recruiting |
| Started | January 20, 2025 |
| Main results expected | May 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | March 10, 2026 |
| Trial ID | NCT07452263 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 70 or older presenting for preoperative work-up at Landspitali and scheduled for major elective non-cardiac surgery are the ideal participants.
✕Probably not a fit
Patients undergoing cardiac surgery, those who do not proceed to their planned surgery, or people younger than 70 are not included and would not directly benefit from this validation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Researchers will administer the modified Essential Frailty Toolset (mEFT)—a brief assessment covering cognition, anemia, serum albumin, and physical function—during preoperative work-up for patients aged 70 and above at Landspitali University Hospital. This is an observational study in which mEFT scores are recorded without changing planned care, and patients who undergo major elective non-cardiac surgery are followed for postoperative outcomes. Outcomes of interest include major postoperative complications, mortality, and 30-day readmission, with analyses comparing mEFT scores to these outcomes to determine predictive performance. Cardiac surgeries and patients who do not proceed to their planned operation are excluded.
Why it matters
Potential benefit: If successful, using the mEFT could give clinicians a quick, practical way to identify older patients at higher surgical risk so care can be tailored to reduce complications and readmissions.
How similar studies have gone: The original Essential Frailty Toolset has shown strong predictive value for mortality and major complications in cardiac surgery populations, but the modified mEFT has not yet been validated in older adults having major elective non-cardiac surgery.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients ≥ 70 years who present for preoperative work-up at the admissions department at Landspitali and undergo frailty screening. * Patients assigned to undergo major surgery Exclusion Criteria: * Cardiac surgery * Not undergoing planned surgery
Where it's running
-
Landspitali University hospital
Reykjavik, Hofudborgarsvaedid, Iceland Recruiting
Study contacts
- Study coordinator: Martin I Sigurdsson, MD, PhD
- Email: mingi@hi.is
- Phone: +354-824-8282
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.