Physical performance monitoring for adults being evaluated for kidney transplant
Physical Performance Assessment in Kidney Transplant Evaluation Using the Short Physical Performance Battery (SPPB)
This project tests whether tracking frailty with the Short Physical Performance Battery (SPPB) before, during, and after kidney transplantation helps predict recovery and outcomes for adults being evaluated for transplant.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Martin Academic / other |
| Locations | 1 site (Martin) |
| Trial ID | NCT07338929 on ClinicalTrials.gov |
What this trial studies
This prospective longitudinal cohort follows adults undergoing kidney transplant evaluation and a comparison group of dialysis patients deemed unsuitable for listing. Participants complete the SPPB at baseline, then annually while waiting, and at 6 and 12 months after transplant for listed patients; ineligible dialysis patients have baseline and annual SPPB measurements. SPPB scores (0–12) will be used to categorize frail, pre-frail, and non-frail status and to compare trajectories between groups. The study links SPPB trajectories with post-transplant outcomes such as graft function and survival to clarify how physical performance changes over time.
Who should consider this trial
Good fit: Adult (≥18) patients undergoing kidney transplant evaluation or dialysis patients (including those not eligible for listing) who can consent and complete the SPPB are appropriate candidates.
Not a fit: Patients with acute medical conditions that prevent reliable SPPB testing or those unable to provide informed consent are unlikely to benefit from participation.
Why it matters
Potential benefit: If successful, the approach could help identify patients at higher risk and guide timing and supportive care to improve transplant recovery and outcomes.
How similar studies have performed: Previous research has shown that SPPB-measured frailty is associated with poorer transplant outcomes, though longitudinal pre- and post-transplant tracking in the same cohort is less commonly reported.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Adult patients (≥18 years) undergoing evaluation for kidney transplantation. 2. Patients on dialysis. 3. Ability and consent to participate. Exclusion Criteria: 1. Non-adult patients. 2. Patients unable to provide informed consent. 3. Acute medical conditions prohibiting SPPB assessment.
Where this trial is running
Martin
- Transplant-nephrology department — Martin, Slovakia (Recruiting)
Study contacts
- Study coordinator: Katarina Sevcikova, MD
- Email: tc@unm.sk
- Phone: +421434203184
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.