Understanding frailty and pre-frailty in older adults

Prevalence, Determinants and Natural History of Frailty and Pre-frailty in People Over the Age of 65 Years in a Prospective 5-year Observation

The Opole University of Technology · NCT04518423

This study looks at how common frailty and pre-frailty are in older adults and how heart health relates to these conditions to help improve care for them.

Quick facts

Study typeObservational
Enrollment1093 (estimated)
Ages65 Years and up
SexAll
SponsorThe Opole University of Technology (other)
Locations1 site (Opole)
Trial IDNCT04518423 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the prevalence, determinants, and natural history of frailty and pre-frailty among elderly individuals. It focuses on a multidimensional approach to frailty, considering physical, psychological, and social factors that contribute to this geriatric syndrome. The study will utilize comprehensive echocardiography to evaluate cardiac function and its relationship with frailty, particularly examining diastolic filling patterns and autonomic nervous system dysfunction. By identifying subclinical cardiovascular abnormalities, the research seeks to enhance prevention and treatment strategies for frailty in older adults.

Who should consider this trial

Good fit: Ideal candidates for this study are community-dwelling elderly individuals over the age of 65 who are able to move around independently.

Not a fit: Patients who are institutionalized, unable to move around, or have terminal diseases with a life expectancy of less than one year may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved identification and management of frailty in elderly patients, potentially enhancing their quality of life and health outcomes.

How similar studies have performed: Other studies have shown success in understanding frailty through multidimensional approaches, indicating that this research builds on established methodologies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Community dwelling elderly individuals over the age of 65 years who get around by themselves.

Exclusion Criteria:

* Institutionalization
* Inability to move around
* Terminal diseases with an anticipated survival of less than 1 year.

Where this trial is running

Opole

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Frailty, Frailty Syndrome, Frail Elderly Syndrome, Fragility, Aging, Aging Problems, Aging Disorder, Aging Well

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.