A study on frailty and dependence in older adults
Official title: Prospective Cohort for the Study of Phenotypic Clusters, Progression Paths and Outcomes of Frailty and Dependence: The Spanish CohorFES
Run by Parc de Salut Mar · NCT06965972 · Data updated 2026-11-12
This study is trying to find out more about frailty in older adults to help doctors spot it early and improve ways to prevent it.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 65 Years to 120 Years |
| Sex | All |
| Enrollment | 1500 (estimated) |
| Sponsor | Parc de Salut Mar Academic / other |
| Locations | 1 site (Barcelona, Catalonia) |
| Status | Recruiting |
| Started | December 1, 2022 |
| Main results expected | December 2030 |
| Study ends | December 31, 2035 |
| Registry record updated | May 11, 2025 |
| Trial ID | NCT06965972 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are men and women aged 65 years or older who are visiting outpatient clinics.
✕Probably not a fit
Patients in critical end-of-life situations or with a Barthel scale score below 60 may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to identify clinical and biological phenotypic clusters associated with frailty syndrome in older adults. It will establish a prospective population-based cohort called CohorFES to facilitate frailty phenotyping and create a biobank for future research. The study will also validate the Frailty Trait Scale 5 (FTS5) as a practical tool for early detection and management of frailty in clinical settings. By understanding the trajectories leading to disability, the study seeks to improve preventive strategies against frailty.
Why it matters
Potential benefit: If successful, this study could lead to improved screening and management of frailty, enhancing the quality of life for older adults.
How similar studies have gone: Other studies have shown success in identifying frailty phenotypes, but this approach aims to fill gaps in clinical settings, making it a novel contribution.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * women and men 65 years old or above visited in the outpatient clinics of participant centers * Signed informed consent Exclusion Criteria: * Patients in a critical situation of end of live or Barthel scale \<60.
Where it's running
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Hospital del Mar Research Institute
Barcelona, Catalonia, Spain Recruiting
Study contacts
- Principal investigator: Xavier Nogues, PhD — Hospital del Mar
- Study coordinator: Natalia Garcia-Giralt, PhD
- Email: ngarcia@researchmar.net
- Phone: 00346160497
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Urinary incontinence in older adults: how leakage and bladder residuals relate to frailty
This study tests whether the severity of urinary leakage and leftover urine after voiding are linked to frailty and other geriatric outcomes in older adults visiting a urology clinic.
-
Combined inspiratory muscle training with blood flow restriction for frail older adults
This study tests whether a short program of breathing muscle training with blood flow restriction is feasible and can improve function in frail older adults.
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Multimodal prehabilitation before elective hip or knee replacement for frail older adults
This program will test whether a tailored multimodal prehabilitation package can help frail adults aged 70 and older who are waiting at least two months for elective hip or knee replacement do better around the time of surgery.
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Conventional Exercise vs Pilates in Prefrail and Frail Older Adults
This study tests whether Pilates or conventional exercise helps improve frailty status and physical function in people aged 60 and older who are prefrail or frail.
-
Modified Essential Frailty Toolset for older adults having major elective non-cardiac surgery
This project will test whether a quick frailty checklist (the modified Essential Frailty Toolset) can predict complications and hospital readmissions in people aged 70 and older scheduled for major elective non-cardiac surgery.
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Quick frailty tests to predict outcomes after elective surgery
This project will test whether quick frailty tests (PRISMA-7, timed up and go, and clock drawing) can predict postoperative outcomes for people 70 and older having intermediate or major elective surgery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.