Clinical trial Recruiting at 1 site Observational Ages 65 to 120

A study on frailty and dependence in older adults

Official title: Prospective Cohort for the Study of Phenotypic Clusters, Progression Paths and Outcomes of Frailty and Dependence: The Spanish CohorFES

Run by Parc de Salut Mar · NCT06965972 · Data updated 2026-11-12

This study is trying to find out more about frailty in older adults to help doctors spot it early and improve ways to prevent it.

Quick facts

Study typeObservational
Ages65 Years to 120 Years
SexAll
Enrollment1500 (estimated)
SponsorParc de Salut Mar
Academic / other
Locations1 site (Barcelona, Catalonia)
StatusRecruiting
StartedDecember 1, 2022
Main results expectedDecember 2030
Study endsDecember 31, 2035
Registry record updatedMay 11, 2025
Trial IDNCT06965972 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are men and women aged 65 years or older who are visiting outpatient clinics.

Probably not a fit

Patients in critical end-of-life situations or with a Barthel scale score below 60 may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to identify clinical and biological phenotypic clusters associated with frailty syndrome in older adults. It will establish a prospective population-based cohort called CohorFES to facilitate frailty phenotyping and create a biobank for future research. The study will also validate the Frailty Trait Scale 5 (FTS5) as a practical tool for early detection and management of frailty in clinical settings. By understanding the trajectories leading to disability, the study seeks to improve preventive strategies against frailty.

Why it matters

Potential benefit: If successful, this study could lead to improved screening and management of frailty, enhancing the quality of life for older adults.

How similar studies have gone: Other studies have shown success in identifying frailty phenotypes, but this approach aims to fill gaps in clinical settings, making it a novel contribution.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* women and men 65 years old or above visited in the outpatient clinics of participant centers
* Signed informed consent

Exclusion Criteria:

* Patients in a critical situation of end of live or Barthel scale \<60.

Where it's running

  • Hospital del Mar Research Institute
    Barcelona, Catalonia, Spain
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.