Condition

Edentulism clinical trials and research

• 16Clinical trials
• 1New in 30 days
• 8Countries

Newest Edentulism clinical trials

All recruiting trials (16)

• Dental Abutments With Different Surfaces in Two-Unit Implant Bridges

  This study tests whether two different abutment surface types affect outcomes for people needing two-implant-supported, two-unit bridges in the back of the mouth.

  Recruiting Kutahya Health Sciences University · Kütahya · NCT07891117

• Accuracy of the Calibrated Framework for Full-Arch Implant Impressions in Edentulous Patients

  This study tests whether digital scanning with a calibrated framework can match the accuracy of traditional splinted impressions for full-arch dental implants in completely toothless patients.

  Recruiting Mansoura University · Al Mansurah · NCT07858682

• Comparison of Non-Calibrated Splinting Scan Bodies and a T-Marker for Full-Arch Implant Scanning

  Researchers are testing two digital methods to record implant positions for full-arch implant-supported prostheses in fully edentulous patients to see which is faster and more accurate.

  Recruiting Menoufia University · Shibīn al Kawm, Shibin Alkom · NCT07723404

• Digital jaw tracking for full-arch maxillary implant restorations

  This randomized trial tests whether using digital jaw tracking to guide the fabrication of full-arch maxillary implant-supported prostheses improves occlusal accuracy and patient satisfaction compared with a conventional workflow.

  Recruiting Mansoura University · Al Mansurah, Dakahlia Governorate · NCT07693946

• Biodontoss and DWC dental implants and superstructures in adults needing tooth replacement

  This PMCF study tests whether BIODENTOSS and DWC dental implants and their superstructures are safe and effective for adults with tooth loss over 24 months.

  Recruiting Değirmenci Otomotiv ve Metal Endüstri A.Ş. · Konya · NCT07633665

• Palatal rugae designs for upper dentures and patient comfort

  We will test three palatal surface designs in upper complete dentures to see if they improve comfort, chewing, speaking, and overall oral quality of life for adults without teeth aged 40 to 80.

  Recruiting Dow University of Health Sciences · Karachi, Sindh · NCT07579377

• Cleaning tools for full-arch implant-supported fixed prostheses

  This test compares Superfloss, interdental brushes, and a water flosser to see which cleans best for people with full-arch implant-supported fixed prostheses.

  Recruiting Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University · Shanghai, Shanghai Municipality · NCT07474493

• Comparing digital mouth scans with traditional denture impressions

  We're testing whether digital mouth scans are as accurate and consistent as traditional border-molded impressions for adults who have lost all their teeth.

  Recruiting Mohammed Bin Rashid University of Medicine and Health Sciences · Dubai · NCT07377890

• How accurate are metal sleeve–free fully guided dental implants?

  This trial will test if metal sleeve–free 3D-printed surgical guides, using two different drill channel sizes in a split-mouth design, place implants accurately in adults needing complete-arch dental rehabilitation.

  Recruiting Universidad Complutense de Madrid · Madrid, Madrid · NCT07364006

• 3D-printed mandibular overdentures made with three different impression techniques

  This trial will test three ways of taking impressions to see which produces the best 3D-printed lower implant overdenture for people without teeth.

  Recruiting Mansoura University · Al Mansurah, Dakahlia Governorate · NCT07208812

• Palatal Rugae Dentures: A New Way to Improve Satisfaction with Complete Dentures

  This study tests whether adding anatomically replicated palatal rugae to upper dentures improves satisfaction and jaw health-related quality of life for adults who are getting new complete dentures.

  Recruiting Phase 2 Pakistan Institute of Medical Sciences · Islamabad, Islamabad · NCT07034079

• Platelet-rich fibrinogen to help socket healing after back-tooth extraction in older adults

  This test will try placing platelet-rich fibrin (PRF) into a posterior tooth extraction site to see if it improves healing in participants aged 14–18 and 50–80 who need a back tooth removed.

  Recruiting University of Nebraska · Lincoln, Nebraska · NCT06943846

• Evaluating different attachments for implant-supported dentures in the lower jaw

  This study is testing which type of attachment, Novaloc or Equator, works better for lower dentures supported by dental implants in patients who have lost all their teeth.

  Recruiting Al-Azhar University · Cairo, Nasr City - Cairo · NCT06721377

• Healing after dental implant placement in patients using TNF-alpha inhibitors

  This study is testing how well dental implants heal in patients taking TNF-alpha inhibitors compared to those who aren't, to see if there are any differences in complications and pain after the procedure.

  Recruiting University of Pennsylvania · Philadelphia, Pennsylvania · NCT06538870

• Comparing one-piece and two-piece ceramic dental implants for tooth loss

  This study is testing whether one-piece or two-piece ceramic dental implants work better for adults with missing teeth and if there are any problems with each type.

  Recruiting at 2 sites CeraRoot SL · Boulder, Colorado and 1 other locations · NCT06287346

• New dental device for replacing missing teeth

  This study is testing a new dental device made of zirconia to see if it can quickly and affordably help people with missing teeth.

  Recruiting Early Phase 1 Bluebird International Clinic · Kathmandu, Bagmati · NCT06018701

Related topics

Quick answers

How many Edentulism clinical trials are recruiting right now?

16, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in Egypt (5 trials), United States (3 trials), Turkey (Türkiye) (2 trials), Spain (2 trials), Pakistan (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Early Phase 1: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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