Evaluating treatment recommendations for children with Burkitt's Lymphoma

Recommendations for the Treatment of Children With Burkitt's Lymphoma

Observational French Africa Pediatric Oncology Group · NCT04425421

This study is trying to find better ways to diagnose and treat children with Burkitt's Lymphoma in Sub-Saharan Africa to improve their chances of recovery.

Quick facts

Study typeObservational
Enrollment1000 (estimated)
AgesN/A to 18 Years
SexAll
SponsorFrench Africa Pediatric Oncology Group Academic / other
Drugs / interventionsrituximab
Locations7 sites (Ouagadougou and 6 other locations)
Trial IDNCT04425421 on ClinicalTrials.gov

What this trial studies

This observational study, led by the French African Pediatric Oncology Group, aims to improve the early diagnosis and treatment response evaluation for children with Burkitt's Lymphoma across at least 14 Sub-Saharan countries. It focuses on children with stage I and II disease, allowing for timely treatment adjustments, and seeks to intensify treatment for those with stage IV disease. By gathering data on treatment outcomes, the study hopes to enhance the overall management of this aggressive cancer in pediatric patients.

Who should consider this trial

Good fit: Ideal candidates for this study are children diagnosed with Burkitt's Lymphoma, particularly those in stages I, II, or IV.

Not a fit: Patients who have previously received treatment for Burkitt's Lymphoma or have other illnesses that complicate treatment may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment protocols and outcomes for children diagnosed with Burkitt's Lymphoma.

How similar studies have performed: Previous studies focusing on Burkitt's Lymphoma treatment have shown promise, but this specific approach of early evaluation and treatment adjustment is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Clinical diagnosis of Burkitt's Lymphoma: all location. Diagnosis by cytology or histology. Not possible to follow all the treatment.

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Exclusion Criteria:

Not a B Cell tumor. Child has been previously treated. Child has also another illness which would render the treatment incompatible. Parents refusal.

Where this trial is running

Ouagadougou and 6 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Burkitt Lymphoma
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.