Condition

Breast Reconstruction clinical trials and research

• 28Clinical trials
• 6NIH research projects
• 1New in 30 days
• 14Countries

Newest Breast Reconstruction clinical trials

All recruiting trials (28)

• ESP Blocks to Help Pain After Breast Reconstruction with Autologous Flaps

  This study tests whether erector spinae plane blocks can improve pain control after autologous free flap breast reconstruction in adults.

  Recruiting Phase 1 Carilion Clinic · Roanoke, Virginia · NCT07891039

• EndoBreast: Feasibility and outcomes of nipple-sparing endoscopic mastectomy with immediate reconstruction

  This observational study tests whether endoscopic nipple-sparing mastectomy with immediate reconstruction is feasible and acceptable for women at risk or with breast cancer.

  Recruiting Azienda Sanitaria Locale Biella · Ponderano, BI · NCT07718425

• Access My Breast Cancer Care App

  A breast cancer care app is being tested to see if it helps patients navigate care, feel more satisfied, and reduce in-person visits.

  Recruiting at 2 sites University of British Columbia · Vancouver, British Columbia and 1 other locations · NCT07696637

• Breast implant study to see how Luna implants perform after surgery

  This study tests whether Eurosilicone Luna breast implants stay intact and keep their shape over 10 years in women aged 18–65 undergoing cosmetic or reconstructive breast surgery.

  Recruiting at 2 sites GCA (Eurosilicone) · Villefranche-sur-Saône and 1 other locations · NCT07679594

• Autologous Fat Grafting vs DIEP flap for reconstructed breast after radiation

  This study tests whether autologous fat transfer can provide similar satisfaction and safety to the DIEP flap procedure for women needing breast reconstruction after mastectomy and radiation.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT07641985

• Prehabilitation with physiotherapy and mechanical stimulation before LD flap breast reconstruction

  This study tests whether prehabilitation with physiotherapy and mechanostimulation improves shoulder pain and mobility for women undergoing breast reconstruction with a latissimus dorsi flap.

  Recruiting Institut du Cancer de Montpellier - Val d'Aurelle · Bordeaux, Aquitaine and 1 other locations · NCT07418060

• Fat grafting plus latissimus dorsi muscle flap for delayed breast reconstruction

  This will try adding fat grafting to a latissimus dorsi muscle flap to rebuild breasts in women who previously had a mastectomy.

  Recruiting Sohag University · Sohag, Sohag Governorate · NCT07331753

• Topical 5% minoxidil to boost blood flow and skin‑flap survival during breast reconstruction

  This trial will test whether applying 5% topical minoxidil to one breast before bilateral risk‑reducing mastectomy with immediate reconstruction improves blood flow and skin‑flap survival compared with a placebo on the other breast.

  Recruiting Phase 1 Duke University · Durham, North Carolina · NCT07264790

• Open versus robotic nipple-sparing mastectomy with immediate DIEP or implant reconstruction

  This trial will test whether robotic-assisted nipple-sparing mastectomy leads to better wellbeing and patient-reported outcomes than standard open nipple-sparing mastectomy in adults having immediate implant or DIEP flap breast reconstruction.

  Recruiting Beaumont Hospital · Beaumont · NCT07230535

• Pectoral versus paravertebral nerve blocks for pain after immediate implant breast reconstruction

  This will test whether paravertebral or pectoral nerve blocks better reduce pain and improve physical well-being for adults having immediate implant-based breast reconstruction.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT07209436

• Hyperbaric Oxygen Therapy to Help Fat Grafts Take in Irradiated Breast

  This trial tests whether breathing pure oxygen in a pressurized chamber helps fat grafts survive better in women who had breast radiation.

  Recruiting University Hospital, Geneva · Geneva, Canton of Geneva · NCT07140198

• OviTex PRS for immediate implant-based breast reconstruction

  This trial will test whether using OviTex PRS is safe and improves outcomes for people having immediate pre-pectoral implant breast reconstruction after mastectomy.

  Recruiting at 3 sites Tela Bio Inc · Tampa, Florida and 2 other locations · NCT07135596

• Hypofractionated radiotherapy after prosthetic breast reconstruction

  This study tests whether a shorter, higher-dose radiotherapy course (HFRT) works as safely and effectively as the standard longer course (CFRT) for patients who had a mastectomy with implant reconstruction.

  Recruiting Phase 3 Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Beijing, Province · NCT07084519

• Implant-based breast reconstruction after bariatric (weight-loss) surgery

  This registry-based project will use national data to see how common breast implants are and whether women who've had bariatric weight-loss surgery have different complication rates after implant-based breast augmentation or reconstruction.

  Recruiting Vastra Gotaland Region · Gothenburg · NCT07059104

• Video education to promote safe opioid use after breast reconstruction

  This trial tests whether a short educational video about opioid use and proper disposal reduces post-discharge opioid use in women having abdominally based autologous free-flap breast reconstruction.

  Recruiting University of Utah · Salt Lake City, Utah · NCT07044583

• Nipple reconstruction with cross-linked hyaluronic acid after mastectomy

  This trial will test whether adding a cross-linked hyaluronic acid injection to areola micropigmentation helps women who had a mastectomy achieve better nipple projection, appearance, and satisfaction.

  Recruiting Germans Trias i Pujol Hospital · Badalona, Barcelona · NCT07008339

• 3D-printed biodegradable breast implants for breast reconstruction

  This study is testing if 3D-printed biodegradable breast implants can improve the look and safety of breast reconstruction for women with newly diagnosed breast cancer compared to traditional methods.

  Recruiting Phase 2 Xijing Hospital · Xi'an, Shaanxi · NCT06993714

• Evaluating prosthetic breast reconstruction after mastectomy

  This study is testing how well two different types of breast reconstruction after mastectomy work for women and how satisfied they are with the results.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna · NCT06774352

• Evaluating a new method for breast reconstruction after mastectomy

  This study is testing a new method for breast reconstruction using the ARTIA Reconstructive Tissue Matrix to see if it works better than the standard care for women who have had a mastectomy.

  Recruiting at 15 sites Phase 3 AbbVie · Los Angeles, California and 22 other locations · NCT06575192

• Evaluating the safety of a new acellular dermal matrix in breast reconstruction

  This study is testing a new type of material used in breast reconstruction surgery to see if it causes fewer complications for women with breast cancer compared to older materials.

  Recruiting DOF Inc. · Seoul, Seoul · NCT06555614

• Investigation of Acellular Dermal Matrix in Breast Reconstruction

  This study is testing if using a special tissue matrix can improve results for women having breast reconstruction surgery with a new technique.

  Recruiting at 12 sites RTI Surgical · Little Rock, Arkansas and 12 other locations · NCT06456554

• Using an antibacterial matrix device for breast reconstruction

  This study is testing whether an antibacterial device can help improve recovery and reduce complications for patients getting breast reconstruction after a mastectomy.

  Recruiting at 10 sites Melodi Health, Inc. · Palo Alto, California and 9 other locations · NCT06027996

• Long-term follow-up of Nagor Perle smooth gel mammary implants

  This project will follow adults who receive Nagor Perle smooth gel breast implants to see if they stay safe and work well over 10 years.

  Recruiting GCA (Eurosilicone) · Manchester · NCT06013514

• Bioimpedance and light-based monitoring during abdominal flap weaning in breast reconstruction

  This study tests a portable bioimpedance device alongside light and temperature measurements to monitor a breast reconstruction flap during arterial and venous weaning in adult women.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT05710705

• Testing a new tissue engineering device for breast reconstruction after cancer surgery

  This study is testing a new device to see if it can safely help women who need breast reconstruction after cancer surgery.

  Recruiting at 3 sites Quanta Medical · Strasbourg, France and 2 other locations · NCT05460780

• Improving recovery after breast reconstruction using autologous tissue

  This study is testing new ways to help women recover better after breast reconstruction surgery using their own tissue, focusing on reducing complications and improving satisfaction.

  Recruiting Vastra Gotaland Region · Gothenburg · NCT05363189

• Comparing fat processing methods for breast reconstruction after mastectomy

  This study is testing which fat processing method works best for keeping fat grafts in place during breast reconstruction after mastectomy for women who have enough fat to use.

  Recruiting Weill Medical College of Cornell University · New York, New York · NCT04891510

• Comparing different acellular dermal matrices for breast reconstruction

  This study is testing which of four different materials used in breast reconstruction helps prevent fluid buildup after surgery in women undergoing this procedure.

  Recruiting at 4 sites University of British Columbia · Vancouver, British Columbia and 3 other locations · NCT04661501

NIH-funded research (6)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• RECONJOINT: A patient-friendly decision tool to help choosing breast reconstruction options with your doctor

  A digital tool helps you share your preferences so your breast reconstruction choices align with what matters most to you during breast cancer care.

  NIH research Sloan-Kettering Inst Can Research · New York, United States · NIH-11286428

• Flexible 3D‑printed biodegradable implants for large breast reconstruction

  A flexible, biodegradable 3D‑printed implant designed to help women who need large‑volume breast reconstruction after cancer surgery.

  NIH research Georgia Institute of Technology · Atlanta, United States · NIH-11248043

• A mobile-friendly breast reconstruction decision tool shared on social media and online groups

  Researchers are sharing a mobile-friendly breast reconstruction decision tool on social media and online communities to help breast cancer patients and survivors learn about options and choose what fits their preferences.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11242072

• Creating a new type of biodegradable implant for breast reconstruction

  This study is testing a new type of biodegradable implant that can help women who need breast reconstruction after cancer surgery, aiming to make the recovery process safer and more effective by better mimicking natural tissue.

  NIH research Georgia Institute of Technology · Atlanta, United States · NIH-11058138

• Improving breast reconstruction decisions for Spanish-speaking Latina women

  This study is creating a helpful tool for Spanish-speaking Latina women who have had a mastectomy due to breast cancer, so they can better understand their options for breast reconstruction and make informed decisions about their care.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11019833

• Using social media to share a breast reconstruction decision tool

  This study is all about helping people who have had a mastectomy, especially those from Black and Hispanic/Latina communities, learn more about their breast reconstruction options using a helpful tool called BREASTChoice, which will be shared through social media to make it easier for everyone to find the information t

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11009967

Related topics

Quick answers

How many Breast Reconstruction clinical trials are recruiting right now?

28, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 14 countries. The most sites are in United States (9 trials), France (4 trials), Spain (2 trials), Sweden (2 trials), Canada (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 2, Phase 3: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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