Clinical trial Recruiting at 1 site Interventional Ages 18 and up Women only

Fat grafting plus latissimus dorsi muscle flap for delayed breast reconstruction

Official title: The Outcomes of Fat Grafting Combined With Latissimus Dorsi Muscle Flap for Delayed Breast Reconstruction After Mastectomy

Run by Sohag University · NCT07331753 · Data updated 2026-11-12

This will try adding fat grafting to a latissimus dorsi muscle flap to rebuild breasts in women who previously had a mastectomy.

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Quick facts

Study typeInterventional
Ages18 Years and up
SexWomen only
Enrollment20 (estimated)
SponsorSohag University
Academic / other
Locations1 site (Sohag, Sohag Governorate)
StatusRecruiting
StartedNovember 1, 2025
Main results expectedNovember 1, 2026
Study endsNovember 1, 2027
Registry record updatedJanuary 12, 2026
Trial IDNCT07331753 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Women indicated for skin-sparing mastectomy who seek delayed autologous breast reconstruction and do not have distant metastatic disease are the intended candidates.

Probably not a fit

Women with stage IV (metastatic) breast cancer or those who are medically unfit for surgery are unlikely to receive benefit from this procedure.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The protocol combines a latissimus dorsi muscle flap with autologous fat grafting to perform delayed breast reconstruction after mastectomy. Eligible women undergo flap reconstruction with simultaneous fat harvest and transfer at Sohag University Hospital. Surgical outcomes such as contour, volume retention, complications, and donor-site morbidity will be recorded during follow-up. The goal is to determine whether the combined technique improves aesthetic results and reduces the need for additional procedures.

Why it matters

Potential benefit: If successful, the approach could provide a more natural breast shape and reduce the need for additional touch-up surgeries.

How similar studies have gone: Similar approaches combining latissimus dorsi flaps with autologous fat grafting have been reported to improve contour and patient satisfaction, though randomized trials are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* female patient indicated for skin sparying mastectomy

Exclusion Criteria:

* female patients with stage 4 breast cancer

Where it's running

  • Sohag university hospital
    Sohag, Sohag Governorate, Egypt
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.