Clinical trial Recruiting at 7 sites Interventional Ages 18 and up

Enhanced DBT skills group for Borderline Personality Disorder

Official title: Effectiveness of Enhanced Dialectical Behavior Therapy Skills Training Group for Borderline Personality Disorder: A Pragmatic, Multicenter, Randomized Non-inferiority Trial

Run by Hospital Dr Sotero del Rio · NCT07875166 · Data updated 2026-11-12

This study tests whether a 12-week DBT skills group helps reduce self-harm and suicidal behavior in people with borderline personality disorder better than a shorter 6-month program or usual care.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment360 (estimated)
SponsorHospital Dr Sotero del Rio
Academic / other
Locations7 sites (Padre Las Casas, Araucania and 6 other locations)
StatusRecruiting
StartedJune 18, 2025
Main results expectedMarch 2027
Study endsApril 2027
Registry record updatedOctober 15, 2026
Trial IDNCT07875166 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with Borderline Personality Disorder who meet at least four SCID-II criteria and who have not had DBT in the last three months, without antisocial personality disorder or active substance use disorder.

Probably not a fit

Individuals with active substance use disorder, antisocial personality disorder, or recent DBT exposure may not experience benefit from these specific interventions.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial compares three approaches to treating BPD in public mental health settings: a 12-week DBT skills training group, a standard 24-week DBT program, and treatment as usual. It aims to determine if the shorter, focused skills group is as good as the longer program and better than usual care in reducing suicidality and self-injury. Participants must meet at least four SCID-II criteria for BPD and have no recent substance use disorder, antisocial personality disorder, or DBT exposure within the past three months. The study is led by Hospital Dr Sotero del Rio with multiple Chilean research partners and sites in Araucanía, Atacama, and Los Lagos regions.

Why it matters

Potential benefit: If successful, participants may experience fewer self-harming behaviors and better overall symptom management with a more accessible treatment format.

How similar studies have gone: Previous DBT research supports its efficacy for BPD, though this study tests a shorter, skills-focused format in Latin American public services, which is relatively novel in this setting.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

\- Meet at least four criteria of BPD according to SCID-II

Exclusion Criteria:

* Antisocial Personality Disorder
* Substance Use Disorder
* Dialectical Behavior Therapy past 3 months

Where it's running

  • CECOSAM Padre Las Casas
    Padre Las Casas, Araucania, Chile
    Recruiting
  • Hospital Provincial del Huasco
    Vallenar, Atacama, Chile
    Recruiting
  • COSAM Puerto Montt
    Port Montt, Los Lagos Region, Chile
    Recruiting
  • COSAM Reloncaví
    Port Montt, Los Lagos Region, Chile
    Recruiting
  • CECOSAM Temuco
    Temuco, Región Del La Araucanía, Chile
    Recruiting
  • COSAM La Pintana
    Santiago, Santiago Metropolitan, Chile
    Recruiting
Show 1 more location
  • Hospital Dr. Sótero del Río
    Santiago, Santiago Metropolitan, Chile
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Left DLPFC rTMS vs iTBS for emotional dysregulation, impulsivity, and NSSI in Borderline Personality Disorder

    This trial tests whether high-frequency rTMS or intermittent theta-burst stimulation over the left DLPFC can help reduce emotional instability, impulsivity, and non-suicidal self-injury in adults with Borderline Personality Disorder.

    Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT07919587

  • Improving Officer and Civilian Health

    This project tests three macro-level approaches—an AI chat assistant for officers, digitized paperwork to reduce arrests for low-level offenses, and a new behavioral health response option—to see if they improve well-being for both officers and civilians in Tarrant County.

    Recruiting Healthy Tarrant County Collaboration · Fort Worth, Texas · NCT07860164

  • Emotional dysregulation in adolescents with complex trauma traits

    Researchers will observe teens to see how emotional dysregulation shows up in CPTSD and how it differs from BPD and PTSD.

    Recruiting University Hospital, Strasbourg, France · Strasbourg, Grand Est · NCT07794332

  • Blended ERITA for Teens Who Self-Injure

    A blended, youth-focused therapy test combines in-person sessions with digital tools to help teens who have recently self-injured see if this approach improves emotion regulation and daily functioning.

    Recruiting Karolinska Institutet · Stockholm · NCT07755774

  • TMS plus Emotion Regulation Skills Training for Borderline Personality Disorder

    This study tests whether adding transcranial magnetic stimulation to emotion regulation skills training helps people with borderline personality disorder improve their ability to manage emotions.

    Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT07714005

  • Gender and Borderline Personality Disorder: a look at relationships and self-view

    This study tests how gender identities relate to relationship experiences and self-perception in people with borderline personality disorder.

    Recruiting University Hospital Heidelberg · Heidelberg · NCT07639957

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.