Internal Family Systems therapy for borderline personality disorder
Official title: Effectiveness of Internal Family Systems Therapy in Improving Mental Health in Individuals With Borderline Personality Disorder
Run by Waypoint Centre for Mental Health Care · NCT07342907 · Data updated 2026-11-12
This pilot will try Internal Family Systems (IFS) therapy to see if it reduces symptoms in people with borderline personality disorder who can participate from Ontario.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 15 (estimated) |
| Sponsor | Waypoint Centre for Mental Health Care Academic / other |
| Locations | 1 site (Tiny, Ontario) |
| Status | Recruiting |
| Started | February 2026 |
| Main results expected | December 2027 |
| Study ends | December 2028 |
| Registry record updated | January 16, 2026 |
| Trial ID | NCT07342907 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are Ontario residents with a confirmed diagnosis of borderline personality disorder who are fluent in English, can commit to up to 50 sessions over 12–15 months, and are not currently receiving other psychotherapy.
✕Probably not a fit
People with current manic or psychotic symptoms, severe substance dependence, significant cognitive or neurological impairment, those unable to commit to the time or cost, or those living outside Ontario are unlikely to be eligible or benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This pilot interventional study will deliver up to 50 individual IFS therapy sessions over about 12–15 months to 15 participants with clinician-confirmed borderline personality disorder. The primary outcome is change in BPD symptom severity from baseline to post-treatment, with secondary measures including emotion dysregulation, shame, self-compassion, interpersonal functioning, mood, addictive behaviors, and overall well-being. The study will also track feasibility outcomes (recruitment, retention, adherence), acceptability, and safety, and excludes people with current manic or psychotic symptoms, severe substance dependence, cognitive impairment, or concurrent psychotherapy. Sessions can be provided virtually across Ontario and participants must be English-fluent and able to commit to the full course of therapy and assessments.
Why it matters
Potential benefit: If successful, IFS could provide an additional psychotherapy option that reduces BPD symptoms, improves emotion regulation and self-compassion, and potentially lowers self-harm and healthcare use.
How similar studies have gone: This is the first trial of IFS specifically for BPD, though other structured psychotherapies like dialectical behavior therapy, mentalization-based therapy, and schema therapy have shown benefits for BPD.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Resident of Ontario, Canada; * Sufficient fluency in English to provide informed consent, participate in therapy sessions, and complete self-reported assessments; * Diagnosis of borderline personality disorder confirmed by a healthcare professional authorized to establish such a diagnosis in Ontario; * Willingness and ability (including financial means) to participate in the 50-session, 12-15-month intervention and the study assessments; * Capacity and willingness to provide written informed consent. Exclusion Criteria: * Current manic or psychotic symptoms regardless of diagnosis; * Substance dependence severe enough to interfere with meaningful level of engagement in the study intervention. * Cognitive impairment or neurological disorders that would preclude informed consent or meaningful participation in the study intervention. * Concurrent participation in any another form of psychotherapy.
Where it's running
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Provincewide across Ontario (intervention can be delivered virtually)
Tiny, Ontario, Canada Recruiting
Study contacts
- Principal investigator: Barna Konkoly-Thege, PhD — Waypoint Centre for Mental Health Care
- Study coordinator: Barna Konkoly-Thege, PhD
- Email: bkonkoly-thege@waypointcentre.ca
- Phone: 705-549-3181
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.