Condition

Bipolar Disorder I or II clinical trials and research

• 6Clinical trials
• 3Countries

Newest Bipolar Disorder I or II clinical trials

All recruiting trials (6)

• FOCUS Bipolar: Families Opening Conversations for Understanding Signs

  This project tests a family-centered screening approach to help identify early signs of bipolar disorder in youth who have a parent with bipolar disorder.

  Recruiting University of Texas Southwestern Medical Center · Dallas, Texas · NCT07622927

• Ketamine with DBT for suicidality in adults with treatment-resistant depression or bipolar disorder and BPD

  This study tests whether four ketamine infusions plus Dialectical Behavioural Therapy can more quickly reduce suicidal thoughts in adults with Borderline Personality Disorder and treatment-resistant depression or bipolar disorder.

  Recruiting Phase 2 University Health Network, Toronto · Toronto, Ontario · NCT07569198

• Using brain scans and machine learning to track emotional ups and downs in bipolar disorder

  This project will test whether fMRI plus machine learning can read moment-by-moment emotions and whether boosting positive emotions can make mood and brain activity more stable in adults with bipolar I or II (currently depressed or mixed) compared with healthy volunteers.

  Recruiting Laureate Institute for Brain Research, Inc. · Tulsa, Oklahoma · NCT07221864

• Ketogenic diet for treating bipolar disorder in adolescents

  This study is testing if a ketogenic diet can help teenagers and young adults with bipolar disorder feel better when combined with their usual medications.

  Recruiting at 2 sites University of California, Los Angeles · Los Angeles, California and 3 other locations · NCT06920940

• Aerobic exercise added to olanzapine‑samidorphan treatment

  This trial will try whether adding four weeks of supervised aerobic exercise to olanzapine‑samidorphan reduces antipsychotic-related weight gain in adults with schizophrenia or bipolar disorders.

  Recruiting Phase 4 New York State Psychiatric Institute · New York, New York · NCT06740890

• Investigating how brain lithium levels affect treatment response in bipolar disorder

  This study is testing if measuring lithium levels in the brain can help predict how well adults with bipolar disorder will respond to lithium treatment.

  Recruiting Leiden University Medical Center · Leiden, South Holland · NCT06134349

Related topics

Quick answers

How many Bipolar Disorder I or II clinical trials are recruiting right now?

6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in United States (4 trials), Netherlands (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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