Condition

Bipolar II Disorder clinical trials and research

• 8Clinical trials
• 4Countries

Newest Bipolar II Disorder clinical trials

All recruiting trials (8)

• Personalized weight-loss medication plan for adults with bipolar disorder

  This pilot tests whether matching FDA-approved weight-loss medicines to specific obesity types helps adults aged 18–65 with bipolar disorder lose weight.

  Recruiting Phase 4 Mayo Clinic · Rochester, Minnesota · NCT07213466

• Personalized closed-loop deep brain stimulation for treatment-resistant Bipolar II depression

  This study will test a personalized closed-loop deep brain stimulation system to try to reduce depressive symptoms in adults with treatment-resistant Bipolar II disorder.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07127913

• Assessing mental health disorders in Hong Kong using a new recall method

  This study is testing a new way to help people in Hong Kong remember important life events to see how many have experienced major depression and thoughts of suicide.

  Recruiting The University of Hong Kong · Hong Kong · NCT06804525

• Assessing the safety and acceptability of psilocybin for Bipolar II depression

  This study is testing if giving two doses of psilocybin along with therapy can be a safe and helpful treatment for people with Bipolar II Disorder who are feeling depressed and suicidal.

  Recruiting Phase 2 The University of Texas Health Science Center, Houston · Houston, Texas · NCT06706232

• Oral icalcaprant for adults with bipolar I or II: safety and symptom change

  This trial will test whether taking oral icalcaprant once daily for six weeks is safe and helps reduce depressive symptoms in adults with bipolar I or II disorder.

  Recruiting at 33 sites Phase 2 AbbVie · Huntsville, Alabama and 32 other locations · NCT06696755

• Synchronized eating for bipolar depression

  This trial will test whether limiting eating to a 10-hour daily window plus usual care helps adults aged 18–55 with bipolar depression compared with nutritional counselling plus usual care.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT06560957

• Comparing lithium and lamotrigine for treating Bipolar II Disorder

  This study is testing whether lithium or lamotrigine works better to stabilize mood in people with Bipolar II Disorder.

  Recruiting Phase 4 University Hospital Bispebjerg and Frederiksberg · Copenhagen · NCT06184581

• Naturalistic treatment and follow-up for youth with bipolar spectrum disorders

  This study looks at young people aged 9 to 19 with bipolar spectrum disorders to see how well they do over a year while receiving standard treatments and tracking their progress.

  Recruiting University of California, Los Angeles · Los Angeles, California and 3 other locations · NCT05427123

Related topics

Quick answers

How many Bipolar II Disorder clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in United States (5 trials), Hong Kong (1 trial), Canada (1 trial), Denmark (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 4: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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