Condition

Alzheimer Disease (AD) clinical trials and research

• 16Clinical trials
• 2NIH research projects
• 1New in 30 days
• 7Countries

Newest Alzheimer Disease (AD) clinical trials

All recruiting trials (16)

• China HEAD: a large community study on healthy aging and dementia

  This study tests whether collecting health, imaging, and biospecimen data from adults in China can help predict who will develop Alzheimer’s disease and related dementias.

  Recruiting at 30 sites Fudan University · Beijing and 29 other locations · NCT07912710

• Home-based gamma-tACS with personalized cognitive training for mild Alzheimer's disease

  This study tests a home-delivered combination of gamma-frequency tACS and individualized memory training to see if it helps people with mild Alzheimer's disease.

  Recruiting IRCCS Centro San Giovanni di Dio Fatebenefratelli · Brescia, Brescia and 1 other locations · NCT07839650

• Gut and Oral Microbiome and Cognitive Health in Aging

  This study tests whether differences in gut and mouth bacteria are linked to cognitive health in adults across ages and cognitive status.

  Recruiting University of South Florida · Tampa, Florida · NCT07799402

• Gut methane and Parkinson's: measuring if a probiotic helps people with Parkinson's, REM sleep behavior disorder, or cognitive concerns

  This study tests whether a probiotic containing Limosilactobacillus reuteri can help people with Parkinson's disease, those at high risk for PD, and related cognitive issues by potentially improving gut methane levels and overall symptoms.

  Recruiting University of Cambridge · Cambridge, CB2 · NCT07786116

• Nicotinamide Riboside by Mouth for Early Alzheimer’s Disease (2-Year Trial)

  This study tests whether taking nicotinamide riboside every day for 24 months can slow progression in adults with early Alzheimer’s disease.

  Recruiting Phase 2 Haukeland University Hospital · Bergen and 1 other locations · NCT07741071

• Rhythmic Auditory Stimulation to Improve Gait and Brain Function in Alzheimer's Disease

  A rhythm-based metronome approach is being tested to see if it helps people with Alzheimer's disease and mild cognitive impairment walk more smoothly and think more clearly.

  Recruiting Boston University Charles River Campus · Boston, Massachusetts · NCT07659964

• CoCoA-PAD: Co-Produced Cognitive Assessment for Preclinical Alzheimer’s Disease

  Researchers are testing a plan where memory nurses help deliver full cognitive assessments to screen for preclinical Alzheimer's disease in people aged 65 and older.

  Recruiting at 2 sites University of Plymouth · Plymouth, Devon and 2 other locations · NCT07598617

• Predicting pre-dementia progression in APOE‑ε4 carriers

  This project will try a combined genetic, blood, and wearable-monitoring model to see if it can predict which cognitively normal or very mildly impaired adults aged 55+ with an APOE‑ε4 gene will develop biomarker-confirmed MCI within 24 months.

  Recruiting Prevention Research Consortium Corp. · San Diego, California · NCT07516119

• Levetiracetam to prevent seizures in adults with Down syndrome and Alzheimer's disease

  This trial will test whether the anti-seizure medicine levetiracetam can prevent tonic-clonic seizures and slow cognitive decline in adults over 40 who have Down syndrome and symptomatic Alzheimer's disease.

  Recruiting Phase 3 Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau · Granada, Andalusia and 4 other locations · NCT07234695

• Daridorexant for preventing Alzheimer disease

  This trial will try nightly daridorexant to see if it helps clear Alzheimer's-linked proteins and protect brain health in adults who do not have dementia.

  Recruiting Phase 2 Douglas Mental Health University Institute · Montreal, Quebec · NCT07213349

• Intravenous umbilical cord blood cell infusion alongside standard Alzheimer's medication

  This trial will try giving an IV infusion of umbilical cord blood mononuclear cells to people aged 50–75 with mild to moderate Alzheimer's alongside their usual medications to see if it helps symptoms or biological disease markers.

  Recruiting Early Phase 1 Anhui Provincial Hospital · Hefei, Anhui · NCT07208344

• DUVAX: a first-in-human vaccine for amyloid and tau targets in adults 40-65

  A first-in-human vaccine called DUVAX is tested in healthy adults to see if it's safe and whether it triggers an immune response against Alzheimer’s-related proteins.

  Recruiting Phase 1 Nuravax, Inc. · Miami Lakes, Florida · NCT07142278

• Brain NAD levels in people with Alzheimer's disease

  This study will try to see if people aged 65–80 with Alzheimer's have lower brain NAD than age-matched people without Alzheimer's by measuring NAD with two MRI-based scans eight months apart.

  Recruiting Florida Atlantic University · Boca Raton, Florida · NCT07127510

• Vagus nerve stimulation to improve cognition in people with mild-to-moderate Alzheimer's disease

  This trial will try implanted vagus nerve stimulation versus a sham procedure in people aged 50–80 with mild-to-moderate Alzheimer's to see if it improves thinking, behavior, and daily functioning at six months.

  Recruiting Beijing Municipal Administration of Hospitals · Beijing · NCT06923007

• Evaluating a new imaging biomarker for neuroinflammation in neurodegenerative diseases

  This study is testing a new imaging tool to see if it can help us understand brain inflammation in people with neurodegenerative diseases like ALS, Alzheimer’s, multiple sclerosis, and Parkinson’s, as well as in healthy volunteers.

  Recruiting at 3 sites Phase 1/2 Ashvattha Therapeutics, Inc. · San Francisco, California and 2 other locations · NCT05395624

• Comprehensive assessment of neurodegeneration and dementia

  This project will collect brain scans, cognitive tests, and biological samples over time to see how dementia and related conditions progress in adults aged 50–90, including people with Parkinson's and people without cognitive problems.

  Recruiting at 11 sites McGill University · Calgary, Alberta and 18 other locations · NCT03402919

NIH-funded research (2)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Reprogramming blood vessel cells to help prevent and treat Alzheimer's disease and hypertension

  This study is looking at how certain cells in your blood vessels might help us understand and improve Alzheimer's disease and high blood pressure, with the hope of finding new ways to boost brain health and blood flow for people dealing with these conditions.

  NIH research University of South Carolina at Columbia · Columbia, United States · NIH-11103308

• A new treatment method for Alzheimer's Disease

  This study is exploring a new way to help people with Alzheimer's by boosting a important substance in the body called NAD+, which might improve brain function and slow down memory loss, using a special method that involves your own blood cells.

  NIH research University of Missouri-Columbia · Columbia, United States · NIH-10740016

Related topics

Quick answers

How many Alzheimer Disease (AD) clinical trials are recruiting right now?

16, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (6 trials), China (3 trials), United Kingdom (2 trials), Canada (2 trials), Italy (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 1/2: 1, Early Phase 1: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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