Cognitive stimulation program for elderly patients with bipolar disorder

Evaluation of Cognitive Stimulation on Dysexecutive Residual Symptoms in Bipolar Patients Over 65 Years of Age

NA · Groupe Hospitalier de la Rochelle Ré Aunis · NCT04184375

This study is testing a special brain training program for older adults with bipolar disorder to see if it can help improve their thinking skills and reduce the chances of them having a relapse.

Quick facts

PhaseNA
Study typeInterventional
Enrollment40 (estimated)
Ages65 Years and up
SexAll
SponsorGroupe Hospitalier de la Rochelle Ré Aunis (other)
Locations1 site (La Rochelle)
Trial IDNCT04184375 on ClinicalTrials.gov

What this trial studies

This study evaluates a cognitive stimulation program specifically adapted for elderly patients with bipolar disorder, focusing on those over 65 years old who experience cognitive impairments. The program aims to enhance cognitive skills, which are crucial for personal development and quality of life, by comparing its effects against standard psychiatric consultations and home nursing interventions. Participants will be assessed for mild to moderate neuro-cognitive impairments and must be in a stable phase of their bipolar condition. The study seeks to determine the effectiveness of cognitive stimulation in improving cognitive function and reducing relapse risks in this population.

Who should consider this trial

Good fit: Ideal candidates are individuals over 65 years old with a long-standing diagnosis of bipolar disorder and mild to moderate cognitive impairments.

Not a fit: Patients who are illiterate, unable to consent, or participating in other therapeutic workshops may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could significantly improve cognitive function and quality of life for elderly patients with bipolar disorder.

How similar studies have performed: Previous studies have shown cognitive stimulation to be beneficial for patients with neurodegenerative diseases, suggesting potential success for this adapted approach in bipolar disorder.

Eligibility criteria

Show full inclusion / exclusion criteria
Pre-Inclusion Criteria:

* age \> 65 years old
* Diagnosis of bipolar illness for more than 10 years
* Euthymic phase
* Understands and speaks French
* Free, informed and express consent

Inclusion Criteria:

* Mild to moderate neuro-cognitive impairments (MMS Test : 16 ≤ score \< 26)

Exclusion Criteria:

* Illiteracy
* Patient participating in other therapeutic workshops (e. g. psycho-geriatric day hospital care, etc.)
* Persons deprived of their liberty by a judicial or administrative decision
* Persons of full age who are subject to a legal protection measure
* Persons unable to consent
* Persons who are not members of or beneficiaries of a social security scheme
* Patient's refusal to participate in the study

Where this trial is running

La Rochelle

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Bipolar Disorder, Cognitive Impairment, Age-related Cognitive Decline

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.