Cognitive stimulation program for elderly patients with bipolar disorder
Official title: Evaluation of Cognitive Stimulation on Dysexecutive Residual Symptoms in Bipolar Patients Over 65 Years of Age
Run by Groupe Hospitalier de la Rochelle Ré Aunis · NCT04184375 · Data updated 2026-11-12
This study is testing a special brain training program for older adults with bipolar disorder to see if it can help improve their thinking skills and reduce the chances of them having a relapse.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 65 Years and up |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Groupe Hospitalier de la Rochelle Ré Aunis Academic / other |
| Locations | 1 site (La Rochelle) |
| Status | Recruiting |
| Started | March 4, 2021 |
| Main results expected | March 3, 2026 |
| Study ends | September 3, 2026 |
| Registry record updated | March 17, 2025 |
| Trial ID | NCT04184375 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals over 65 years old with a long-standing diagnosis of bipolar disorder and mild to moderate cognitive impairments.
✕Probably not a fit
Patients who are illiterate, unable to consent, or participating in other therapeutic workshops may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates a cognitive stimulation program specifically adapted for elderly patients with bipolar disorder, focusing on those over 65 years old who experience cognitive impairments. The program aims to enhance cognitive skills, which are crucial for personal development and quality of life, by comparing its effects against standard psychiatric consultations and home nursing interventions. Participants will be assessed for mild to moderate neuro-cognitive impairments and must be in a stable phase of their bipolar condition. The study seeks to determine the effectiveness of cognitive stimulation in improving cognitive function and reducing relapse risks in this population.
Why it matters
Potential benefit: If successful, this program could significantly improve cognitive function and quality of life for elderly patients with bipolar disorder.
How similar studies have gone: Previous studies have shown cognitive stimulation to be beneficial for patients with neurodegenerative diseases, suggesting potential success for this adapted approach in bipolar disorder.
Who can join: the full rules
Show full inclusion / exclusion criteria
Pre-Inclusion Criteria: * age \> 65 years old * Diagnosis of bipolar illness for more than 10 years * Euthymic phase * Understands and speaks French * Free, informed and express consent Inclusion Criteria: * Mild to moderate neuro-cognitive impairments (MMS Test : 16 ≤ score \< 26) Exclusion Criteria: * Illiteracy * Patient participating in other therapeutic workshops (e. g. psycho-geriatric day hospital care, etc.) * Persons deprived of their liberty by a judicial or administrative decision * Persons of full age who are subject to a legal protection measure * Persons unable to consent * Persons who are not members of or beneficiaries of a social security scheme * Patient's refusal to participate in the study
Where it's running
-
Groupe Hospitalier de la Rochelle Ré Aunis
La Rochelle, France Recruiting
Study contacts
- Study coordinator: Caroline ALLIX-BEGUEC, Ph.D.
- Email: caroline.allix-beguec@ght-atlantique17.fr
- Phone: +33 (0) 516 49 42 46
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Biomarkers That Signal Silent Strokes in High-Risk Cardiac Procedures
This study tests whether blood biomarkers NSE and NFLs can predict silent brain injuries and later cognitive problems in adults having high-risk transcatheter heart procedures.
-
Blood-based tests and digital cognitive checks to help triage dementia
This study tests whether adding blood biomarkers, APOE4 genetic info, and digital cognitive tests can help dementia diagnosis be faster in NHS Memory Clinics.
-
Cardiovascular and Cognitive Health Initiative
This study tests whether targeted cognitive and heart-health interventions can help improve thinking skills in adults with cardiovascular disease.
-
Synbiotic blend of LA-5 and agave inulin for mild cognitive impairment
This pilot crossover study tests whether a synbiotic containing Lactobacillus acidophilus LA-5 and agave inulin can help adults aged 60–75 with mild cognitive impairment.
-
Immediate vs progressive standing dual-task training for older adults with mild to moderate cognitive impairment
This study tests whether starting with immediate standing dual-task training is better or worse than progressively increasing the difficulty for older adults with mild to moderate cognitive impairment.
-
Can a phone version of the Mini-Cog identify cognitive impairment before surgery?
This study tests whether a telephone-based Mini-Cog can reliably detect cognitive impairment in adults 65 and older before they have surgery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.