Condition

Cushing Syndrome clinical trials and research

• 15Clinical trials
• 12Countries

Newest Cushing Syndrome clinical trials

All recruiting trials (15)

• Myokines in metabolic and endocrine diseases linked to sarcopenia

  This study tests whether myokines can serve as biomarkers or drivers of sarcopenia and sarcopenic obesity in people with metabolic or endocrine diseases.

  Recruiting Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Woluwe-Saint-Pierre - Sint-Pieters-Woluwe · NCT07703683

• Osilodrostat for high blood pressure caused by Cushing's syndrome

  This study tests whether osilodrostat can lower high blood pressure in adults with Cushing's syndrome-related hypercortisolemia.

  Recruiting at 3 sites Phase 4 Recordati Group · Jacksonville, Florida and 2 other locations · NCT07247162

• Normal ranges and diagnostic cut-offs for salivary cortisol

  This project will test two saliva cortisol methods — a lab LC‑MS assay and a rapid fluorescence immunoassay — to find normal ranges and the best diagnostic cut-offs for adults with suspected Cushing syndrome or adrenal insufficiency.

  Recruiting Shanghai 6th People's Hospital · Shanghai, Shanghai Municipality · NCT07168122

• Using modified Desmopressin for better imaging in Cushing syndrome

  This study is testing a new way to use a modified form of Desmopressin to improve imaging for people with Cushing syndrome, helping doctors better see and understand pituitary tumors before surgery.

  Recruiting Post Graduate Institute of Medical Education and Research, Chandigarh · Chandigarh · NCT06962202

• Impact of Metyrapone on Heart Health in Patients with Adrenal Issues

  This study is testing if Metyrapone can improve heart health and lower blood pressure in people with adrenal problems like incidentalomas and subclinical Cushing's syndrome.

  Recruiting at 3 sites Phase 4 IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna and 2 other locations · NCT06801249

• Improving the Desmopressin test for diagnosing Cushing Syndrome

  This study is testing a new way to use the Desmopressin test to better diagnose different types of Cushing syndrome in adults who might have the condition.

  Recruiting Phase 2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT06635629

• Registry for Rare Diseases

  This study is creating a detailed registry to collect information on rare diseases like amyloidosis and sarcoidosis to help improve how they are diagnosed and treated.

  Recruiting Hospital Italiano de Buenos Aires · Buenos Aires, Buenos Aires · NCT06573723

• Comparing recovery after adrenal surgery with and without drainage tubes

  This study is testing whether having surgery for adrenal problems without drainage tubes helps patients recover faster and feel less pain compared to traditional surgery with tubes.

  Recruiting Zhongnan Hospital · Wuhan, Hubei · NCT06250699

• Investigating the effects of Cushing's syndrome on fatty liver disease

  This study is testing how Cushing's syndrome affects the risk of developing fatty liver disease in adults who have the condition.

  Recruiting at 7 sites University Hospital, Angers · Angers and 6 other locations · NCT05881005

• Observing patients with Cushing's syndrome before and after treatment

  This study looks at how Cushing's syndrome affects people's daily lives and health before and after they receive treatment to see if things get better.

  Recruiting University of Aarhus · Aarhus, State · NCT05521529

• Understanding recovery from Cushing syndrome after surgery

  This study looks at how people with Cushing syndrome recover after surgery and whether a special biofeedback program can help with symptoms after stopping steroid treatment.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT04543253

• Circadian Gene Changes in People with Glucocorticoid Disorders

  This study tests whether circadian gene expression in blood cells differs between people with glucocorticoid disorders and healthy controls.

  Recruiting University of Roma La Sapienza · Roma, Roma · NCT04374721

• Evaluating osilodrostat for children with Cushing's syndrome

  This study is testing if a new medication called osilodrostat can help children and teens with Cushing's syndrome feel better and manage their symptoms.

  Recruiting at 4 sites Phase 2 Recordati Group · San Francisco, California and 14 other locations · NCT03708900

• Collecting information on treatment results for patients with Cushing's syndrome

  This study is collecting information from people with Cushing's syndrome during their regular treatment to see how the condition affects their quality of life and mental health over time.

  Recruiting at 7 sites Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 6 other locations · NCT03364803

• Investigating adrenal tumors and their treatments

  This study looks at adrenal tumors and their treatments to see how they develop and what therapies might help patients feel better.

  Recruiting University of Wuerzburg · Würzburg · NCT00669266

Related topics

Quick answers

How many Cushing Syndrome clinical trials are recruiting right now?

15, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 12 countries. The most sites are in United States (5 trials), Italy (3 trials), Belgium (2 trials), China (2 trials), France (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 4: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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