Spinal Mobility, Rigidity, and Kinesiophobia in Parkinson's Disease with and without TMD
Official title: A Comparative Study of Spinal Mobility, Axial Rigidity, and Kinesiophobia Between Parkinson's Disease Patients With and Without Temporomandibular Disorders
Run by Mustafa Kemal University · NCT07850674 · Data updated 2026-11-12
This study tests whether people with Parkinson's disease who have Temporomandibular Disorders differ in spinal mobility, axial rigidity, and kinesiophobia from those without TMD.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 35 Years to 75 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Mustafa Kemal University Academic / other |
| Locations | 1 site (Hatay) |
| Status | Recruiting |
| Started | September 23, 2026 |
| Main results expected | December 23, 2026 |
| Study ends | December 30, 2026 |
| Registry record updated | October 5, 2026 |
| Trial ID | NCT07850674 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with Parkinson's disease aged 40–75, at Hoehn and Yahr stages 1.5–4, with MMSE ≥ 24, evaluated in the ON state.
✕Probably not a fit
PD patients without TMD or with severe comorbidities may not experience a clear benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study will compare adults with Parkinson's disease, aged 40–75, who are in Hoehn and Yahr stages 1.5–4, to see if the presence of Temporomandibular Disorders affects spinal mobility, axial rigidity, and fear of movement (kinesiophobia). Assessments will be conducted in person at the Neurology Outpatient Clinic of Hatay Mustafa Kemal University, during the medicated “ON” state. Data will explore potential biomechanical links between TMJ function and trunk control in PD, contributing to understanding of how jaw and spine mechanics may interact in this population.
Why it matters
Potential benefit: If differences are found, results could help guide physical therapy approaches that address both TMJ and spinal mobility in PD.
How similar studies have gone: Previous work has shown links between PD-related rigidity and craniofacial function; this study adds observational data on TMD co-occurrence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosed with Parkinson's disease * Modified Hoehn \& Yahr stages 1.5 to 4 * Mini-Mental State Examination (MMSE) score ≥ 24 * Evaluated during the medication "ON" state Exclusion Criteria: * History of cervical, lumbar, maxillofacial, or temporomandibular joint surgery -Acute orthopedic or severe rheumatologic disease (e.g., advanced ankylosing spondylitis) * Additional comorbid neurological disorders (e.g., stroke, multiple sclerosis) * Complete edentulism or severe disruption of oral anatomy * Ongoing acute dental pain * Pregnancy or suspected pregnancy * Severe psychiatric disorders
Where it's running
-
Hatay Mustafa Kemal Universty
Hatay, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: derya yavuz demiray
- Email: deryayavuz149@gmail.com
- Phone: +90 5305146831
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.