How physical activity might help people with Parkinson’s disease who have DBS-STN implants

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study examines whether a program of physiotherapy and education about physiotherapy can improve motor and non-motor symptoms in people with idiopathic Parkinson’s disease who are treated with DBS-STN. Eligible participants are adults aged 50 to 70 with Hoehn and Yahr stages II–IV and suitable for advanced DBS-STN therapy. The trial focuses on late-stage symptoms such as gait impairment and postural instability, aiming to complement DBS-STN with physical activity. Interventions include structured physiotherapy sessions and education to promote ongoing physical activity. Outcomes will be evaluated to determine if the combined approach improves quality of life and functional mobility compared with standard care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients diagnosed with idiopathic Parkinson's disease (ICD-10:G20).
* Patients qualified for advanced therapies using DBS-STN.
* Grade II-IV on the Hoehn \& Yahr scale.
* Age 50-70.
* Consent to participate in the study.

Exclusion Criteria:

* Patients diagnosed with atypical parkinsonism.
* Patients not eligible for advanced therapies with DBS-STN.
* Hoehn \& Yahr Grade I and V.
* Age \<50 and \>70
* Patients diagnosed with dementia syndrome (MMSE \< 24/30).
* Diseases of the osteoarticular system and muscles that make it impossible to undergo rehabilitation.
* Severe kidney, liver and heart failure.
* Active malignancy or malignancy diagnosed and treated within 3 years prior to the study.

Where it's running

• Department of Neurology, Faculty of Health Sciences, Bródnowski Mazovian Hospital
  Warsaw, Poland Recruiting

Study contacts

• Study coordinator: Marta M Betka, PhD student
• Email: marta.maria.betka@gmail.com
• Phone: 48798789277

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.