Strength and dual-task training to help people with Parkinson’s improve strength and function

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, parallel-group randomized trial with three arms comparing different physiotherapy interventions for sarcopenia-related outcomes in adults with Parkinson’s disease or parkinsonian syndromes. Participants are assigned to an Education Group, Progressive Resistance Training (PRT) with cognitive dual-task, or PRT with cognitive dual-task plus instability training. The study integrates nutrition education and supervised exercise, with outcomes focusing on muscle strength, body composition, physical performance, and related domains. Eligibility includes adults with PD or parkinsonism, Hoehn and Yahr 1-3, stable medication, and ability to walk. The lead sponsor is the University of Valencia, with collaboration from CLÍNICA NYR, and the trial is conducted at Clínica NYR in Valencia.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Clinical diagnosis of Parkinson's disease or parkinsonism confirmed by a neurologist.
* Hoehn and Yahr stage 1-3.
* Age ≥18 years.
* Stable antiparkinsonian drug treatment for at least the previous 4 weeks.
* Ability to ambulate independently, with or without assistive devices.
* Ability to understand and follow basic safety instructions.

Exclusion Criteria:

* Severe or uncontrolled additional pathology.
* Other neurological diseases that interfere with the assessment.
* Recent fractures.
* Severe dyskinesias or unpredictable motor fluctuations that compromise safety.
* Any medical condition that contraindicates supervised physical exercise

Where it's running

• Clínica NYR
  Valencia, Valencia, Spain Recruiting

Study contacts

• Principal investigator: Anna Arnal Gómez, PhD — Department of Physiotherapy, University of Valencia
• Study coordinator: Anna Arnal Gómez, PhD
• Email: anna.arnal@uv.es
• Phone: +34 963983853

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.