Registry for Spontaneous Coronary Artery Dissection

The "Virtual" Multicenter Spontaneous Coronary Artery Dissection (SCAD) Registry

Observational Mayo Clinic · NCT01429727

This study is trying to gather information about people with Spontaneous Coronary Artery Dissection to better understand the condition and improve treatment and prevention.

Quick facts

Study typeObservational
Enrollment2500 (estimated)
Ages18 Years and up
SexAll
SponsorMayo Clinic Academic / other
Locations1 site (Rochester, Minnesota)
Trial IDNCT01429727 on ClinicalTrials.gov

What this trial studies

This project aims to describe the clinical and physiological characteristics of Spontaneous Coronary Artery Dissections (SCAD) to enhance awareness, understanding, treatment, and prevention of this serious cardiovascular condition. The study involves both retrospective and prospective reviews of the medical histories and current health of individuals diagnosed with SCAD. By building a comprehensive database of SCAD patients, the research seeks to identify patterns in incidence, causes, and associations that could inform future studies and improve patient outcomes.

Who should consider this trial

Good fit: Ideal candidates include individuals diagnosed with SCAD, particularly women who are pregnant or postpartum, underrepresented racial or ethnic groups, men, and younger patients.

Not a fit: Patients with a history of SCAD who do not meet the updated inclusion criteria may not benefit from this study.

Why it matters

Potential benefit: If successful, this registry could lead to better understanding and management of SCAD, ultimately improving patient care and outcomes.

How similar studies have performed: While SCAD is a relatively novel area of research, the establishment of registries for rare conditions has shown promise in other studies, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Individuals who have been cared for at Mayo Clinic with a diagnosis of SCAD
* SCAD in women who are pregnant or within 12 months postpartum at the time of SCAD
* SCAD in individuals who self-identify as a member of a racial or ethnic group that is currently underrepresented in the registry. This would include anyone who identifies as: Black/African American, Asian, American Indian or Alaska Native, Native Hawaiian or Other Pacific Islander, and any race with Hispanic ethnicity
* SCAD in a man
* SCAD in persons younger than 30 years of age
* SCAD within the past 2 weeks (acute)
* SCAD patient enrolling into any other Mayo Clinic SCAD Research Study
* SCAD in individuals who have a relative that has had a SCAD event

Persons with history of SCAD who are interested in participating in the study but do not meet the updated inclusion criteria will not be enrolled at this time. However, they will be given the option to share their contact information in order to be invited to future Mayo Clinic SCAD studies.

Where this trial is running

Rochester, Minnesota

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Spontaneous Coronary Artery DissectionSCADSpontaneous coronary artery dissectioncoronary artery diseasemyocardial infarctioncoronary dissection
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.