Clinical trial Recruiting at 3 sites Observational Ages 18 and up

Norwegian SCAD follow-up and outcomes program

Official title: Norwegian Spontaneous Coronary Artery Dissection Study (NOR-SCAD Study)

Run by Oslo University Hospital · NCT07317323 · Data updated 2026-11-12

This program will follow adults hospitalized with SCAD in Norway for one year to see if scheduled imaging, tests, and questionnaires identify complications and risk factors.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment300 (estimated)
SponsorOslo University Hospital
Academic / other
Locations3 sites (Bergen and 2 other locations)
StatusRecruiting
StartedApril 1, 2025
Main results expectedDecember 31, 2035
Study endsDecember 31, 2035
Registry record updatedJanuary 5, 2026
Trial IDNCT07317323 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (≥18 years) hospitalized with angiographically or imaging-confirmed spontaneous coronary artery dissection at participating Norwegian hospitals are ideal candidates.

Probably not a fit

People with severe kidney failure, severe allergic reactions to contrast, or those not hospitalized with confirmed SCAD are unlikely to benefit from this program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

NOR-SCAD is a multicenter prospective observational cohort enrolling adults hospitalized with angiographically or imaging-confirmed spontaneous coronary artery dissection at major Norwegian hospitals from 2025–2035. Participants are followed for 52 weeks with planned in-person visits at about 8 and 12 weeks and a final phone call at 52 weeks. Evaluations include coronary CT angiography (CTA), cardiac exams, cardiopulmonary exercise testing (CPET), genetic analyses, blood sampling, and structured questionnaires. Primary endpoints are incidence and types of complications and major adverse cardiac events (MACE), with a secondary focus on the diagnostic and follow-up utility of coronary CTA.

Why it matters

Potential benefit: If successful, this could help clinicians detect post-SCAD complications earlier and better guide follow-up care to reduce recurrent cardiac events.

How similar studies have gone: Other national and international SCAD registries have improved knowledge of patient characteristics and outcomes, but routine coronary CTA as a follow-up tool remains incompletely tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Spontaneous coronary artery dissection

Exclusion Criteria:

* Severe kidney failure
* Severe allergic reaction to contrast

Where it's running

  • Haukeland University Hospital
    Bergen, Norway
    Recruiting
  • Akershus University Hospital
    Oslo, Norway
    Recruiting
  • Rikshospitalet, Oslo University Hospital
    Oslo, Norway
    Recruiting

Study contacts

  • Principal investigator: Mette Elise Estensen, MD., PhD — ProCardio, Kardiologisk avdeling Rikshospitalet, Oslo Univeristy Hospital
  • Study coordinator: Anna Louise Astad Sørlie, MD
  • Email: anloso@ous-hf.no
  • Phone: +47 926 55 483

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.