Observational study on spontaneous coronary artery dissection

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Canadian SCAD Study is a multicenter, prospective observational registry aimed at understanding the natural history of spontaneous coronary artery dissection (SCAD) and its associated conditions. This study will enroll 3,000 patients over a 10-year follow-up period, focusing on the demographics, predisposing factors, and treatment strategies for SCAD. By collecting data from major cardiac centers across Canada and internationally, the study seeks to address the gaps in knowledge regarding SCAD, which often affects young women and is frequently misdiagnosed. The findings will help inform future randomized controlled trials and improve management strategies for SCAD patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients admitted with ACS (STEMI, NSTEMI or unstable angina)
2. Documented SCAD on a coronary angiogram (including diagnosis with OCT or IVUS)

Exclusion Criteria:

1\. Patients where SCAD is attributed to atherosclerotic coronary artery disease, with atherosclerotic coronary artery disease stenosis ≥50%

Where it's running

• Vancouver General Hospital
  Vancouver, British Columbia, Canada Recruiting

Study contacts

• Principal investigator: Jacqueline Saw, MD — Cardiology Research UBC / Vancouver General Hospital
• Study coordinator: Andrew Starovoytov, MD
• Email: a.starovoytov@ubc.ca
• Phone: 6048755079

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Exercise responses in people with spontaneous coronary artery dissection or fibromuscular dysplasia

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• Genetic causes of spontaneous coronary artery dissection

  This project will test whether inherited or new gene changes cause spontaneous coronary artery dissection in adults with SCAD and their biological relatives.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT01427179

• Norwegian SCAD follow-up and outcomes program

  This program will follow adults hospitalized with SCAD in Norway for one year to see if scheduled imaging, tests, and questionnaires identify complications and risk factors.

  Recruiting at 3 sites Oslo University Hospital · Bergen and 2 other locations · NCT07317323

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.