Clinical trial Recruiting at 1 site Interventional Ages 18 and up Women only

Comparing different techniques to treat endometriosis

Official title: Histologic Comparison of Ablative Techniques for Endometriosis - a Randomized Trial

Run by TriHealth Inc. · NCT06414083 · Data updated 2026-11-12

This study is testing different methods to treat endometriosis, like laser and heat techniques, to see which one works best for relieving pain in women who are already having surgery for the condition.

Quick facts

Study typeInterventional
Ages18 Years and up
SexWomen only
Enrollment141 (estimated)
SponsorTriHealth Inc.
Academic / other
Locations1 site (Cincinnati, Ohio)
StatusRecruiting
StartedMay 9, 2024
Main results expectedMay 9, 2025
Study endsJune 9, 2025
Registry record updatedMay 30, 2024
Trial IDNCT06414083 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adult women aged 18 and older who are planning to undergo surgery for endometriosis-related symptoms.

Probably not a fit

Patients who are pregnant at the time of enrollment or surgery will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to directly compare the effectiveness of various ablative techniques, including diathermy, CO2 laser, and argon beam coagulator, in treating endometriosis. By evaluating their ability to destroy native endometriosis tissue in human subjects, the research seeks to identify the most effective method for alleviating endometriosis-related pain. The study will involve adult women who are already scheduled for robotic-assisted or laparoscopic excision of endometriosis lesions. This comparison is significant as it addresses a gap in existing research regarding the effectiveness of these technologies.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment options for women suffering from endometriosis and its associated pain.

How similar studies have gone: This study is novel as there have been no direct comparisons of these ablative techniques in human subjects to date.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult women 18 years of age or older
* Already planning to undergo scheduled robotic assisted or laparoscopic excision of lesions for pelvic pain symptoms (pelvic pain, dysmenorrhea, dyspareunia, dysuria, dyschezia, ovarian pain) or endometriosis of any kind (endometriosis of any location, or endometrioma)

Exclusion Criteria:

* Known pregnancy at enrollment or at the time of the excision surgery

Where it's running

  • Good Samaritan Hospital
    Cincinnati, Ohio, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.