Comparing different techniques to treat endometriosis
Histologic Comparison of Ablative Techniques for Endometriosis - a Randomized Trial
This study is testing different methods to treat endometriosis, like laser and heat techniques, to see which one works best for relieving pain in women who are already having surgery for the condition.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 141 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | TriHealth Inc. Academic / other |
| Locations | 1 site (Cincinnati, Ohio) |
| Trial ID | NCT06414083 on ClinicalTrials.gov |
What this trial studies
This study aims to directly compare the effectiveness of various ablative techniques, including diathermy, CO2 laser, and argon beam coagulator, in treating endometriosis. By evaluating their ability to destroy native endometriosis tissue in human subjects, the research seeks to identify the most effective method for alleviating endometriosis-related pain. The study will involve adult women who are already scheduled for robotic-assisted or laparoscopic excision of endometriosis lesions. This comparison is significant as it addresses a gap in existing research regarding the effectiveness of these technologies.
Who should consider this trial
Good fit: Ideal candidates for this study are adult women aged 18 and older who are planning to undergo surgery for endometriosis-related symptoms.
Not a fit: Patients who are pregnant at the time of enrollment or surgery will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment options for women suffering from endometriosis and its associated pain.
How similar studies have performed: This study is novel as there have been no direct comparisons of these ablative techniques in human subjects to date.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult women 18 years of age or older * Already planning to undergo scheduled robotic assisted or laparoscopic excision of lesions for pelvic pain symptoms (pelvic pain, dysmenorrhea, dyspareunia, dysuria, dyschezia, ovarian pain) or endometriosis of any kind (endometriosis of any location, or endometrioma) Exclusion Criteria: * Known pregnancy at enrollment or at the time of the excision surgery
Where this trial is running
Cincinnati, Ohio
- Good Samaritan Hospital — Cincinnati, Ohio, United States (Recruiting)
Study contacts
- Study coordinator: Devin Namaky, MD
- Email: devin_namaky@trihealth.com
- Phone: 513-862-1888
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.