Partial pulpotomy in mature lower molars with SIP using calcium hypochlorite vs sodium hypochlorite

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized trial compares two wound lavage solutions, 2.5% calcium hypochlorite and 2.5% sodium hypochlorite, used after removing a small portion of inflamed pulp in mature permanent mandibular molars with symptomatic irreversible pulpitis. Outcomes include clinical and radiographic success at 6 and 12 months, as well as patient-reported pain and oral health-related quality of life over time. Eligibility focuses on adults 18–40 with deeply carious, restorable molars and controlled inflammation. The study aims to determine which lavage agent better supports pulpal healing while preserving tooth structure. It is conducted at PGIDS Rohtak with a randomized allocation to the two intervention arms.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. patients aged 18-40 years
2. Mature permanent mandibular molars with extremely deep caries (caries penetrating the entire thickness of the dentine radiographically, without radiopaque zone separating lesion from the pulp) and clinical diagnosis of SIP with PAI score ≤ 2
3. Periodontally healthy teeth (probing pocket depth ≤3 mm and mobility within normal limit)
4. Patients having physical status of class 1 or 2 according to ASA classification
5. Pulpal bleeding could be controlled within 10 min following pulp amputation

Exclusion Criteria:

1. Non restorable teeth
2. No pulp exposure even after complete caries excavation
3. Necrotic or partially necrotic pulp upon exposure
4. Presence of sinus tract or soft tissue swelling
5. Radiographic signs of internal or external root resorption
6. Pregnant women

Where it's running

• Pgids
  Rohtak, Haryana, India Recruiting

Study contacts

• Principal investigator: Dr Mayank Arora, MDS — PGIDS, Rohtak, 124001
• Study coordinator: Dr. Mayank Arora, MDS
• Email: dr.arora002@gmail.com
• Phone: +918295964200

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Using intraoral cold to improve numbness in lower front teeth

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.