Direct pulp capping in lower molars with side (proximal) versus top (occlusal) cavities: does the cavity location matter?

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants aged 15–40 with mature permanent mandibular molars, extremely deep caries and clinical signs of reversible pulpitis will receive direct pulp capping and be grouped by lesion location (proximal versus occlusal). Clinical outcomes will be recorded at 7 days, 6 months and 12 months, and radiographic outcomes will be assessed at 6 and 12 months. Oral health–related quality of life and postoperative pain will be measured at baseline and daily for one week after the procedure. The trial compares success rates and patient-reported outcomes between the two lesion-location groups to see if location affects the effectiveness of this conservative treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Mature permanent mandibular molars with extremely deep caries that penetrate the entire thickness of dentine as detected on radiograph with reversible pulpitis will be included.
2. Participant with Reversible pulpitis will be diagnosed clinically based on discomfort experienced by the participant when a stimulus such as cold or sweet is applied and goes away within a couple of seconds following the removal of the stimulus, with no significant radiographic changes in the periapical region of the suspect tooth and the pain experienced is not spontaneous.
3. The pulpal sensibility will be confirmed through positive response to electric and cold tests (Endo frost) and the presence of bleeding after caries excavation. 4.Pulpal and the periapical diagnosis will be established based on the diagnostic terminology approved by American Association of Endodontists (AAE, 2019).

5.Teeth with a negative response to palpation and percussion testing and radiographic finding of periapical index (PAI) score ≤2 and healthy periodontium (probing pocket depth ≤3 mm and mobility within normal limit) will be included. 6.Teeth in which hemostasis achieved within 5 mins will be included.

7.Only pulp exposures with size 0.5-1 mm will be included

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Exclusion Criteria:

1. Mechanical or pulp exposure due to trauma
2. absence of exposure after excavation of caries
3. failure to achieve hemostasis within 5 mins
4. irreversible pulpitis and teeth having periapical lesions
5. periodontal disease, resorptive defects, calcified canals, as assessed by radiographic examination will serve as criteria for exclusion.
6. Also immunocompromised, Pregnant and subjects having systemic diseases will be excluded -

Where it's running

• PGIDS Rohtak, Rohtak, Haryana 124001
  Rohtak, Haryana, India Recruiting

Study contacts

• Principal investigator: Dr. Pankaj Sangwan, MDS — PGIDS, Rohtak, 124001
• Study coordinator: Dr. Pankaj Sangwan, MDS
• Email: drps_1@yahoo.co.in
• Phone: +919996112202

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Direct pulp capping for deep and extremely deep caries in mature molars with reversible pulpitis

  This study tests whether direct pulp capping works similarly for deep versus extremely deep caries in adult, mature mandibular molars with reversible pulpitis.

  Recruiting Postgraduate Institute of Dental Sciences Rohtak · Rohtak, Haryana · NCT07696702

• Pulpal inflammation and full pulpotomy outcomes in deeply carious mandibular molars

  This study tests whether levels of inflammatory markers IL-1β and IL-6 in deeply decayed mandibular molars predict the success of a full pulpotomy in adults with moderate to severe pulpitis.

  Recruiting Postgraduate Institute of Dental Sciences Rohtak · Rohtak, Haryana · NCT07825415

• Partial pulpotomy in mature lower molars with SIP using calcium hypochlorite vs sodium hypochlorite

  This trial tests whether washing the exposed pulp with calcium hypochlorite or with sodium hypochlorite during partial pulpotomy in adults helps healing and reduces pain.

  Recruiting Postgraduate Institute of Dental Sciences Rohtak · Rohtak, Haryana · NCT07748676

• Using pulpal blood biomarkers to predict success of vital pulp therapy in symptomatic teeth

  This trial will test whether measuring metabolic biomarkers in pulpal blood at the time of carious pulp exposure can help predict 12-month success of vital pulp treatment in people aged 16–50 with symptomatic deep caries.

  Recruiting University of Baghdad · Baghdad · NCT07452614

• Pulpotomy versus root canal treatment for extremely deep caries

  This study tests whether full pulpotomy works as well as root canal treatment for people aged 12 and older with extremely deep caries treated in a university dental clinic.

  Recruiting National University Hospital, Singapore · Singapore · NCT07242742

• Partial pulpotomy outcomes for mature molars with moderate versus severe pulpitis

  We will try partial pulpotomy in people aged 15–40 who have mature permanent molars with moderate or severe pulpitis to see if the results differ.

  Recruiting Postgraduate Institute of Dental Sciences Rohtak · Rohtak, Haryana · NCT07123025

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.