Clinical trial Recruiting at 1 site Observational Ages Any age to 18

Investigating ventilation practices in critically ill children

Official title: PRactice of VENTilation in Critically Ill PEDiatric Patients (PRoVENT-PED) - an International Multicenter Observational Study

Run by University Medical Center Groningen · NCT06220825 · Data updated 2026-11-12

This study looks at how doctors are using breathing machines for critically ill children in hospitals to see if different practices can improve their recovery and survival rates.

Quick facts

Study typeObservational
AgesAny age to 18 Years
SexAll
Enrollment2500 (estimated)
SponsorUniversity Medical Center Groningen
Academic / other
Locations1 site (Groningen)
StatusRecruiting
StartedApril 1, 2024
Main results expectedApril 1, 2034
Study endsApril 1, 2034
Registry record updatedFebruary 7, 2025
Trial IDNCT06220825 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are critically ill pediatric patients aged 0-18 who require ventilatory support for more than 12 hours.

Probably not a fit

Patients who are premature infants or do not require prolonged ventilatory support will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This international observational study aims to explore current ventilation practices in critically ill pediatric patients across various pediatric intensive care units. It will collect detailed data on ventilatory support, including duration, ICU stay, and mortality rates, over a span of 10 years. The study seeks to identify modifiable factors related to ventilation that may influence patient outcomes, addressing a significant gap in knowledge as much of the existing data is derived from adult patient experiences. Data will be gathered during specific 4-week periods each year, with flexibility for centers to opt out as needed.

Why it matters

Potential benefit: If successful, this study could lead to improved ventilation strategies and better outcomes for critically ill pediatric patients.

How similar studies have gone: While studies on adult ventilation practices have shown success, this approach in pediatric patients is relatively novel and underexplored.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Expected use of (non-)invasive respiratory support for at least 12 hrs

Exclusion Criteria:

* premature infants (i.e., postconceptional age corrected for gestational age \< 40 weeks)

Where it's running

  • UMC Groningen
    Groningen, Netherlands
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.