Investigating ventilation practices in critically ill children
PRactice of VENTilation in Critically Ill PEDiatric Patients (PRoVENT-PED) - an International Multicenter Observational Study
This study looks at how doctors are using breathing machines for critically ill children in hospitals to see if different practices can improve their recovery and survival rates.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2500 (estimated) |
| Ages | N/A to 18 Years |
| Sex | All |
| Sponsor | University Medical Center Groningen Academic / other |
| Locations | 1 site (Groningen) |
| Trial ID | NCT06220825 on ClinicalTrials.gov |
What this trial studies
This international observational study aims to explore current ventilation practices in critically ill pediatric patients across various pediatric intensive care units. It will collect detailed data on ventilatory support, including duration, ICU stay, and mortality rates, over a span of 10 years. The study seeks to identify modifiable factors related to ventilation that may influence patient outcomes, addressing a significant gap in knowledge as much of the existing data is derived from adult patient experiences. Data will be gathered during specific 4-week periods each year, with flexibility for centers to opt out as needed.
Who should consider this trial
Good fit: Ideal candidates are critically ill pediatric patients aged 0-18 who require ventilatory support for more than 12 hours.
Not a fit: Patients who are premature infants or do not require prolonged ventilatory support will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved ventilation strategies and better outcomes for critically ill pediatric patients.
How similar studies have performed: While studies on adult ventilation practices have shown success, this approach in pediatric patients is relatively novel and underexplored.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Expected use of (non-)invasive respiratory support for at least 12 hrs Exclusion Criteria: * premature infants (i.e., postconceptional age corrected for gestational age \< 40 weeks)
Where this trial is running
Groningen
- UMC Groningen — Groningen, Netherlands (Recruiting)
Study contacts
- Principal investigator: Martin CJ Kneyber, MD PhD — University Medical Center Groningen
- Study coordinator: Relin Van Vliet, MSc
- Email: r.vanvliet@amsterdamumc.nl
- Phone: 0031627560257
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.