Helping smokers practice quitting tobacco

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to address tobacco use disorder by exploring a novel approach called practice quitting (PQ), which encourages smokers to attempt not smoking for short periods without the pressure of a permanent quit date. It will compare the effectiveness of PQ counseling against Motivational Interviewing (MI) counseling, alongside the provision of nicotine replacement therapy (NRT) samples. The study will involve 780 current smokers who are not planning to quit in the next 30 days, evaluating the impact of these interventions on the incidence of quit attempts over six months.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Eligible participants will be males and females who:

1. are 18 years or older
2. report current daily cigarette smoking (≥ 5 cigarettes per day)
3. are not planning to quit in the next 30 days
4. are not currently engaged in smoking cessation treatment
5. are motivated to quit or engage in a non-cessation goal (i.e., reduce smoking, learn more about treatment options, and/ or try out skills to change smoking) in the next 6 months
6. are English speaking
7. reside in the continental United States
8. have access to a smartphone that can be used to complete study procedures

Exclusion Criteria:

Participants will be excluded for daily vaping/ electronic cigarettes use (i.e., use for ≥ 25 days within past 30 days) and any FDA contraindications for NRT use if they:

1. are pregnant/breastfeeding
2. had recent cardiovascular trauma such as myocardial infarction
3. had a stroke within the past 3 months

Where it's running

• Rush University Medical Center
  Chicago, Illinois, United States Recruiting

Study contacts

• Principal investigator: Amanda Mathew, PhD — Rush University Medical Center
• Study coordinator: Maritza Esqueda-Medina
• Email: on-deq@rush.edu
• Phone: 312-563-3702

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.