Clinical trial Recruiting at 1 site Observational Ages 18 and up

Documenting opioid use and pain management after surgery

Official title: Pain and Opioids After Surgery (PANDOS) Study

Run by University of Aberdeen · NCT05877157 · Data updated 2026-11-12

This study looks at how opioids are used for pain management after surgery in adults to see how it affects their recovery and quality of life over time.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment10000 (estimated)
SponsorUniversity of Aberdeen
Academic / other
Locations4 sites (Zagreb, Vinogradska 29 and 3 other locations)
StatusRecruiting
StartedSeptember 25, 2023
Main results expectedMay 30, 2026
Study endsSeptember 30, 2026
Registry record updatedDecember 24, 2024
Trial IDNCT05877157 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are hospitalized adults aged 18 and older undergoing any inpatient surgery during the designated study week.

Probably not a fit

Patients classified as ASA grade V or VI, or those unable to provide informed consent, may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to collect data on perioperative opioid use and its safety across hospitals in the UK and Europe. It will involve hospitalized adult patients undergoing surgery during a designated week, with follow-ups at one week, three months, and twelve months post-surgery. The primary focus is on opioid use three months after surgery, while secondary outcomes include preoperative pain, persistent pain, and quality of life. The study seeks to understand the relationship between opioid use and surgical complications.

Why it matters

Potential benefit: If successful, this study could improve pain management strategies and reduce opioid-related complications for surgical patients.

How similar studies have gone: Other studies have explored opioid use in postoperative settings, indicating potential for meaningful insights, though this specific approach may be novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* hospitalised adult patients (18 years and older) undergoing any inpatient surgery (elective or emergency) during the designated study week where an anaesthetist is involved (general anaesthetic, sedation, local anaesthetic).

Able to understand and has capacity to give written informed consent

Exclusion Criteria:

* American Society of Anaesthesiologists (ASA) grade V or VI
* Refusal to participate.
* Lack of comprehension of validated questionnaires or inability to complete the follow-up for any reason.
* Lack of capacity to give written informed consent

Where it's running

  • NHS Grampian
    Aberdeen, United Kingdom
    Recruiting
  • Department of Anaesthesiology Sestre Milosrdnice, University Hospital Center
    Zagreb, Vinogradska 29, Croatia
    Not yet recruiting
  • University College London Hospitals NHS Foundation Trust
    London, United Kingdom
    Active not recruiting
  • Kings Mill Hospital, Sherwood Forest Hospitals NHS Foundation Trust
    Nottingham, United Kingdom
    Active not recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.