Documenting opioid use and pain management after surgery
Official title: Pain and Opioids After Surgery (PANDOS) Study
Run by University of Aberdeen · NCT05877157 · Data updated 2026-11-12
This study looks at how opioids are used for pain management after surgery in adults to see how it affects their recovery and quality of life over time.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | University of Aberdeen Academic / other |
| Locations | 4 sites (Zagreb, Vinogradska 29 and 3 other locations) |
| Status | Recruiting |
| Started | September 25, 2023 |
| Main results expected | May 30, 2026 |
| Study ends | September 30, 2026 |
| Registry record updated | December 24, 2024 |
| Trial ID | NCT05877157 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are hospitalized adults aged 18 and older undergoing any inpatient surgery during the designated study week.
✕Probably not a fit
Patients classified as ASA grade V or VI, or those unable to provide informed consent, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to collect data on perioperative opioid use and its safety across hospitals in the UK and Europe. It will involve hospitalized adult patients undergoing surgery during a designated week, with follow-ups at one week, three months, and twelve months post-surgery. The primary focus is on opioid use three months after surgery, while secondary outcomes include preoperative pain, persistent pain, and quality of life. The study seeks to understand the relationship between opioid use and surgical complications.
Why it matters
Potential benefit: If successful, this study could improve pain management strategies and reduce opioid-related complications for surgical patients.
How similar studies have gone: Other studies have explored opioid use in postoperative settings, indicating potential for meaningful insights, though this specific approach may be novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * hospitalised adult patients (18 years and older) undergoing any inpatient surgery (elective or emergency) during the designated study week where an anaesthetist is involved (general anaesthetic, sedation, local anaesthetic). Able to understand and has capacity to give written informed consent Exclusion Criteria: * American Society of Anaesthesiologists (ASA) grade V or VI * Refusal to participate. * Lack of comprehension of validated questionnaires or inability to complete the follow-up for any reason. * Lack of capacity to give written informed consent
Where it's running
-
NHS Grampian
Aberdeen, United Kingdom Recruiting -
Department of Anaesthesiology Sestre Milosrdnice, University Hospital Center
Zagreb, Vinogradska 29, Croatia Not yet recruiting -
University College London Hospitals NHS Foundation Trust
London, United Kingdom Active not recruiting -
Kings Mill Hospital, Sherwood Forest Hospitals NHS Foundation Trust
Nottingham, United Kingdom Active not recruiting
Study contacts
- Principal investigator: Patrice Forget — University of Aberdeen
- Study coordinator: Patrice Forget
- Email: patrice.forget@abdn.ac.uk
- Phone: 01224437285
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.