Documenting opioid use and pain management after surgery
Pain and Opioids After Surgery (PANDOS) Study
This study looks at how opioids are used for pain management after surgery in adults to see how it affects their recovery and quality of life over time.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 10000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Aberdeen Academic / other |
| Locations | 4 sites (Zagreb, Vinogradska 29 and 3 other locations) |
| Trial ID | NCT05877157 on ClinicalTrials.gov |
What this trial studies
This observational study aims to collect data on perioperative opioid use and its safety across hospitals in the UK and Europe. It will involve hospitalized adult patients undergoing surgery during a designated week, with follow-ups at one week, three months, and twelve months post-surgery. The primary focus is on opioid use three months after surgery, while secondary outcomes include preoperative pain, persistent pain, and quality of life. The study seeks to understand the relationship between opioid use and surgical complications.
Who should consider this trial
Good fit: Ideal candidates are hospitalized adults aged 18 and older undergoing any inpatient surgery during the designated study week.
Not a fit: Patients classified as ASA grade V or VI, or those unable to provide informed consent, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve pain management strategies and reduce opioid-related complications for surgical patients.
How similar studies have performed: Other studies have explored opioid use in postoperative settings, indicating potential for meaningful insights, though this specific approach may be novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * hospitalised adult patients (18 years and older) undergoing any inpatient surgery (elective or emergency) during the designated study week where an anaesthetist is involved (general anaesthetic, sedation, local anaesthetic). Able to understand and has capacity to give written informed consent Exclusion Criteria: * American Society of Anaesthesiologists (ASA) grade V or VI * Refusal to participate. * Lack of comprehension of validated questionnaires or inability to complete the follow-up for any reason. * Lack of capacity to give written informed consent
Where this trial is running
Zagreb, Vinogradska 29 and 3 other locations
- Department of Anaesthesiology Sestre Milosrdnice, University Hospital Center — Zagreb, Vinogradska 29, Croatia (Not_yet_recruiting)
- NHS Grampian — Aberdeen, United Kingdom (Recruiting)
- University College London Hospitals NHS Foundation Trust — London, United Kingdom (Active_not_recruiting)
- Kings Mill Hospital, Sherwood Forest Hospitals NHS Foundation Trust — Nottingham, United Kingdom (Active_not_recruiting)
Study contacts
- Principal investigator: Patrice Forget — University of Aberdeen
- Study coordinator: Patrice Forget
- Email: patrice.forget@abdn.ac.uk
- Phone: 01224437285
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.