Dexa vs Dexmedetomidine with Bupivacaine in TAP Block for Laparotomy Analgesia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults aged 25–65 undergoing laparotomy are randomized to receive a TAP block with bupivacaine plus either dexamethasone or dexmedetomidine as adjuvants. The blocks are performed bilaterally under ultrasound guidance at the end of surgery, with standard monitoring and consent procedures in place. Outcomes will focus on analgesia duration, time to first rescue analgesia, and total postoperative analgesic use. The trial is conducted at Sahiwal Teaching Hospital under the lead sponsorship of Sahiwal Medical College, with ethical approvals governing the two parallel groups of 48 patients each.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients undergoing laparotomy.
* Patients aged 25 to 65 years.
* Both genders.
* Patients with ASA Class I, II.

Exclusion Criteria:

* Patients who do not give consent.
* Patients with Comorbidities like DM, HTN, CKD, CLD.
* Patients with bleeding disorders.
* Infection at site of injection.
* Allergy to any drug, local anaesthetic, or other drugs used.
* Patients with polytrauma.

Where it's running

• Sahiwal Medical College
  Sahiwal, Punjab Province, Pakistan Recruiting

Study contacts

• Study coordinator: Dr Maryam Mumtaz, MBBS
• Email: Maryamsumra3@gmail.com
• Phone: 00923336238201

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Autonomic Nerve Blockade to Reduce Pain and Nausea After Bariatric Surgery

  This study tests whether an autonomic nerve block given during bariatric surgery can lessen pain and nausea and decrease the need for anti-nausea and pain medicines in the first 72 hours after sleeve gastrectomy or gastric bypass.

  Recruiting Endeavor Health · Evanston, Illinois · NCT07104825

• Comparing pain relief methods after knee surgery

  This study is testing which pain relief method, Adductor Canal Block or Genicular Nerve Block, works better for people aged 18-72 after knee surgery.

  Recruiting Başakşehir Çam & Sakura City Hospital · Istanbul · NCT06909851

• Using the Nociception Level Index to guide opioid dosing during combined regional and general anesthesia

  This trial tests whether using a Nociception Level Index (NOL) monitor to guide opioid dosing during combined general and regional anesthesia can reduce opioid use and side effects for adults having elective trauma or orthopedic surgery.

  Recruiting Universitätsklinikum Hamburg-Eppendorf · Hamburg · NCT06905340

• Comparing ketamine delivery methods for postoperative pain management in orthopedic surgery

  This study is testing whether giving ketamine through an IV or a patient-controlled pump works better for managing pain after major orthopedic surgery in adults.

  Recruiting Phase 4 Universidad de Antioquia · Medellín, Antioquia · NCT06774274

• Comparing pain relief methods after lumbar fusion surgery

  This study tests whether a new way of giving local anesthesia during lumbar fusion surgery can help patients feel less pain and use fewer opioids compared to the traditional method.

  Recruiting University of Massachusetts, Worcester · Worcester, Massachusetts · NCT06528288

• Smart opioid dispenser and app for patients having a one-level lumbar discectomy or laminectomy

  This test tries a locked opioid-dispensing device plus a smartphone app to help adults having a one-level lumbar discectomy or laminectomy who are opioid-naive or occasional users take oxycodone more safely after discharge.

  Recruiting Hospital for Special Surgery, New York · New York, New York · NCT06358040

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.