Pre-incisional ropivacaine plus Diprospan for pain after laparoscopic surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional trial compares pre-incisional infiltration of ropivacaine with and without Diprospan in adults undergoing elective laparoscopic cholecystectomy, appendectomy, or hernia repair. The approach targets incision-area inflammation to extend analgesia after surgery. Participants are adults 18–64 with ASA I–III who can consent and comply with follow-up. Primary goals are to see if adding Diprospan can prolong pain relief and improve post-op comfort compared with ropivacaine alone. The study is conducted at Beijing Tiantan Hospital with a lead sponsor from the same institution.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients scheduled for elective Laparoscopic Surgery for laparoscopic cholecystectomy, appendectomy, or hernia repair under general anesthesia;
2. Ages 18 to 64 years old;
3. American Society of Anesthesiologists (ASA) physical status of I-III;
4. Patients must be able to understand nature and potential personal; consequences of the clinical trial and cooperation with follow-up investigations;
5. signing of the informed consent form.

Exclusion Criteria:

1. History of allergies to experimental drugs such as opioids or steroids;
2. Alcohol abuse; Long term use of opioid drugs (exceeding 2 weeks or 3 days per week for more than 1 month); Suspected use of sedatives and analgesics;
3. Use analgesic drugs within 24 hours before surgery;
4. Patients undergoing steroid therapy;
5. Serious neurological disorders, severe liver and kidney dysfunction, heart failure, etc;
6. Unable to use pain assessment scale;
7. Pregnant or lactating patients.

Where it's running

• Beijing Tiantan Hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Study coordinator: Fang Luo
• Email: 13611326978@163.com
• Phone: +86 13611326978

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Pre-incisional ropivacaine plus triamcinolone for pain after laparoscopic surgery

  This trial tests whether injecting ropivacaine with or without triamcinolone before incision can reduce postoperative pain in adults undergoing common laparoscopic procedures like gallbladder removal, appendix removal, or hernia repair.

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality · NCT07591233

• Subcostal TAP Block and EEG Changes During Laparoscopic Gallbladder Surgery

  This observational study tests whether adding a subcostal TAP block to standard IV opioid therapy affects intraoperative brain activity measures and pain needs in adults undergoing laparoscopic cholecystectomy.

  Recruiting Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital · Istanbul · NCT07818954

• Dexmedetomidine vs magnesium as intraperitoneal add-ons to bupivacaine for laparoscopic gallbladder removal

  This study tests whether adding dexmedetomidine or magnesium sulfate to bupivacaine injected inside the abdomen provides better pain relief after laparoscopic cholecystectomy for adults without serious health issues.

  Recruiting Alexandria University · Alexandria · NCT07693621

• How different ventilator settings affect lung energy during gallbladder surgery

  This study tests whether two ventilator modes (VCV and PRVC) deliver different amounts of energy to the lungs in adults undergoing laparoscopic gallbladder removal.

  Recruiting Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital · Yenimahalle, Ankara · NCT07670494

• Erector Spinae Plane Block with Low-Flow Anaesthesia in Laparoscopic Cholecystectomy

  This trial tests whether a nerve block done before surgery plus very low-flow anesthesia reduces pain and opioid use after gallbladder removal.

  Recruiting Taksim Egitim ve Arastirma Hastanesi · Istanbul · NCT07653490

• Pre-incisional ropivacaine plus diprospan to relieve pain after VATS

  This study tests whether injecting ropivacaine with diprospan before surgery can reduce postoperative pain for adults and children undergoing VATS lung surgery.

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality · NCT07626489

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.