Clinical trial Recruiting at 1 site Interventional Ages 30 to 65

Erector Spinae Plane Block vs Modified Thoracoabdominal Nerve Block After Laparoscopic Cholecystectomy

Official title: Erector Spinae Plane Block Versus Modified Thoracoabdominal Nerve Block For Pain Control After Laparoscopic Cholecystectomy

Run by Alexandria University · NCT07624058 · Data updated 2026-11-12

Two regional anesthesia techniques are being tested to see which provides better pain control after gallbladder removal surgery.

Quick facts

Study typeInterventional
Ages30 Years to 65 Years
SexAll
Enrollment50 (estimated)
SponsorAlexandria University
Academic / other
Locations1 site (Alexandria)
StatusRecruiting
StartedApril 1, 2026
Main results expectedDecember 1, 2026
Study endsMarch 1, 2027
Registry record updatedJune 3, 2026
Trial IDNCT07624058 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 30-65 undergoing laparoscopic cholecystectomy, with ASA physical status I–III and BMI 18–35 kg/m2.

Probably not a fit

Patients with contraindications to regional anesthesia, skin infection at injection sites, coagulopathy, diabetes mellitus, or refusal to participate may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial compares bilateral erector spinae plane (ESP) block with bilateral modified thoracoabdominal (M-TAPA) nerve block for postoperative analgesia following laparoscopic cholecystectomy. It aims to determine which block offers more effective and balanced pain relief by targeting different nerve pathways and dermatomal coverage. The study builds on the shift toward ultrasound-guided regional anesthesia within multimodal pain strategies to reduce opioid use and enhance recovery after surgery. Outcomes of interest include analgesic efficacy, opioid consumption, and recovery-related measures in adults undergoing LC. The design focuses on direct comparison in a real-world surgical setting at a single institution.

Why it matters

Potential benefit: If successful, patients may experience better pain control with less opioid use after gallbladder surgery.

How similar studies have gone: Regional anesthesia techniques like ESPB and M-TAPA have shown promise in various abdominal surgeries, but head-to-head data in LC are limited and this comparison is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age: between 30 - 65
* American Society of Anaesthesiologists physical status: I- III
* Body mass index: 18-35 kg.m-2

Exclusion Criteria:

* Patient Refusal
* Allergy to local anaesthetic agents.
* Skin infection at the site of injection.
* Coagulopathy.
* Diabetes Mellitus

Where it's running

  • Alexandria University
    Alexandria, Egypt
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.