Erector Spinae Plane Block with Low-Flow Anaesthesia in Laparoscopic Cholecystectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this randomized trial, patients undergoing elective laparoscopic cholecystectomy receive an ultrasound-guided erector spinae plane block combined with low-flow anesthesia and are compared to standard anesthesia care. The study looks at postoperative recovery quality, pain scores, analgesic needs, and perioperative outcomes using QoR-15 as a primary measure. The ESP block targets thoracic levels to provide somatic and visceral analgesia, potentially enhancing recovery and reducing opioid requirements. The design reflects a multimodal approach to postoperative pain management in a common surgical procedure.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged 18-65 years
* ASA physical status I-II
* Body mass index (BMI) \<35 kg/m²
* Scheduled for elective laparoscopic cholecystectomy
* Ability to provide written informed consent

Exclusion Criteria:

* Coagulopathy or bleeding disorders
* Allergy to local anaesthetic agents
* Infection at the block application site
* Neurological or psychiatric disorders
* Communication difficulties
* Chronic opioid or analgesic use
* Reoperation cases
* Acute cholecystitis
* Conversion to open surgery
* Inadequate dermatomal block after ESPB
* Severe intraoperative hemodynamic instability
* Intraoperative blood loss ≥250 mL
* Development of allergic reactions or major complications during follow-up

Where it's running

• Taksim Training and Research Hospital
  Istanbul, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Leyla SIVACIGIL, MD — Taksim Training and Research Hospital
• Study coordinator: Leyla Sivacigil, MD
• Email: veralleyla@hotmail.com
• Phone: 90 5065983478

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.