Comparing three surgical techniques for treating lumbar spinal stenosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to compare the clinical efficacy of three surgical techniques—Endo-Surgi Plus endoscopic, Unilateral Biportal Endoscopic (UBE), and microdiscectomy—in treating lumbar spinal stenosis. It involves a multicenter approach where patients diagnosed with single-segment lumbar spinal stenosis will be randomly assigned to one of the three surgical groups. The study will evaluate differences in surgical outcomes, complications, and recovery aspects among the techniques. Postoperative care includes low-dose medications and rehabilitation exercises to ensure proper recovery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosed with single-segment lumbar spinal stenosis through CT and MRI imaging combined with clinical symptoms;
* Symptoms in the lumbar region and lower extremities corresponding to the imaging findings;
* Patients who have not responded to three months of conservative treatment;
* Informed consent from family members regarding the surgical procedure and associated risks.

Exclusion Criteria:

* Patients with multi-segment lumbar disc herniation, malignant spinal tumors, spinal deformities, and other diseases.
* Patients with comorbidities such as cardiovascular diseases, cerebrovascular diseases, or those with mental abnormalities, communication difficulties, or other issues that may affect clinical evaluation.
* Patients with a history of previous lumbar surgery.

Where it's running

• Qilu Hospital of Shandong University
  Jinan, Shandong, China Recruiting

Study contacts

• Study coordinator: Xinyu Yang, M.D.
• Email: dr_xinyuyang@163.com
• Phone: +8618560089496

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Effect of Irrigation Pressure on Postoperative Complications and Surgical Field Clarity in Unilateral Biportal Endoscopic Spine Surgery

  This study tests whether the height of the irrigation fluid bag and the direction of the surgical cut affect fluid pressure, visibility, and early recovery in adults undergoing unilateral biportal endoscopic spine surgery.

  Recruiting First Affiliated Hospital of Kunming Medical University · Kunming, Yunnan · NCT07837427

• Microdecompression alone vs. decompression with fusion in adjacent segment stenosis

  This trial tests whether a less invasive microdecompression can work as well as adding a fusion extension for people with adjacent segment stenosis after prior lumbar fusion.

  Recruiting Charite University, Berlin, Germany · Berlin, State of Berlin · NCT07661199

• Comparison of two TLIF procedures for single-level lumbar spinal stenosis

  This trial tests two minimally invasive TLIF procedures (LUSE-TLIF and MIS-TLIF) to see which better helps people with single-level lumbar spinal stenosis who have not improved with non-surgical treatments.

  Recruiting The Third Affiliated Hospital of Southern Medical University · Guangzhou, Guangdong · NCT07588555

• Opioid-free versus opioid-based anesthesia for elective lumbar spine surgery

  This test compares opioid-free multimodal anesthesia (with or without an erector spinae plane block) against opioid-containing anesthesia in adults having elective lumbar spine surgery to see which controls pain better and reduces opioid need in the first 48 hours after surgery.

  Recruiting Marmara University · Istanbul, Maltepe · NCT07489001

• Prevalence of PAD in Patients With Surgically Treated Lumbar Spinal Stenosis

  This study tests how common peripheral artery disease is in people who have lumbar spinal stenosis and are being considered for, or have had, surgery.

  Recruiting Rennes University Hospital · Lille and 2 other locations · NCT07469020

• Decompressive laminectomy alone versus laminectomy with transpedicular screw fixation for lumbar spinal stenosis

  Adults age 30–60 with multilevel lumbar spinal stenosis who haven't improved after six weeks of non-surgical care will be randomly assigned to decompressive laminectomy alone or to laminectomy plus transpedicular screw fixation to see which option relieves pain, improves function, and gives better spinal stability.

  Recruiting Early Phase 1 Punjab Health Care Commission · Lahore, Punjab Province · NCT07281625

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.