Decompressive laminectomy alone versus laminectomy with transpedicular screw fixation for lumbar spinal stenosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial will enroll 60 adults aged 30–60 with MRI-confirmed multilevel lumbar spinal stenosis who failed at least six weeks of conservative treatment. Participants will be randomized to decompressive laminectomy alone or decompressive laminectomy with transpedicular screw fixation and followed for postoperative outcomes. Primary measures include operative time, postoperative complications, length of stay, pain by VAS at baseline, day 7 and 3 months, and function by ODI at baseline and 3 months, with radiographs used to assess spinal stability and fusion at 3 months. The single-center trial will be conducted at the Department of Neurosurgery, Services Institute of Medical Sciences in Lahore over a six-month recruitment period.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 30-60 years
* Diagnosis of lumbar spinal stenosis based on MRI criteria (anteroposterior canal diameter \<10-15 mm or cross-sectional area \<75-145 mm²)
* Multilevel disc herniation
* Degenerative disc disease with Pfirrmann grade 3-5 on T2-weighted MRI
* Failure of at least six weeks of conservative treatment

Exclusion Criteria:

* Previous history of lumbar spine surgery
* Spinal malignancy
* Congenital lumbar spinal stenosis, scoliosis, or kyphoscoliosis
* Lumbar spondylolisthesis grade 3-5
* Significant comorbidities including diabetes mellitus or ischemic heart disease

Where it's running

• Services Institute of Medical Sciences
  Lahore, Punjab Province, Pakistan Recruiting

Study contacts

• Principal investigator: Hira Umar, MBBS — Sims Siut
• Study coordinator: Hira Umar, MBBS
• Email: quickcareclinicdr03@gmail.com
• Phone: +92 317 4226862

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.