Effect of Irrigation Pressure on Postoperative Complications and Surgical Field Clarity in Unilateral Biportal Endoscopic Spine Surgery
Official title: Effect of Irrigation Pressure on Postoperative Complications and Surgical Field Clarity in Unilateral Biportal Endoscopic Surgery
Run by First Affiliated Hospital of Kunming Medical University · NCT07837427 · Data updated 2026-11-12
This study tests whether the height of the irrigation fluid bag and the direction of the surgical cut affect fluid pressure, visibility, and early recovery in adults undergoing unilateral biportal endoscopic spine surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | First Affiliated Hospital of Kunming Medical University Academic / other |
| Locations | 1 site (Kunming, Yunnan) |
| Status | Recruiting |
| Started | February 5, 2026 |
| Main results expected | December 2027 |
| Study ends | January 2028 |
| Registry record updated | September 23, 2026 |
| Trial ID | NCT07837427 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18–75 years scheduled for unilateral biportal endoscopic surgery for lumbar degenerative disease at the specified hospital.
✕Probably not a fit
Patients not experiencing improvements in irrigation pressure or surgical field visibility with the studied adjustments may not experience additional benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This single-center, randomized trial will enroll about 80 adults aged 18 to 75 with lumbar degenerative disease who are scheduled for UBE surgery. Participants will be randomly assigned to one of four groups combining two fluid bag heights (0.9 m or 1.0 m) and two incision directions (horizontal or vertical) to examine effects on irrigation pressure, surgical field clarity, blood loss, and early postoperative pain and function. Disc tissue collected during surgery will be analyzed to explore relationships between disc degeneration and factors such as sex, age, mechanical stress, and injury. The study is designed to generate prospective clinical evidence on how controllable intraoperative factors influence outcomes in UBE procedures. Data will be collected at a single center, with follow-up of at least six months.
Why it matters
Potential benefit: If successful, the findings could guide surgeons on optimal irrigation setup and incision direction to improve visibility, reduce bleeding, and enhance early recovery after UBE surgery.
How similar studies have gone: Prospective studies have explored irrigation parameters in minimally invasive spine surgery, but this specific factorial assessment of bag height and incision direction in UBE is novel/less established.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \>= 18 years and \< 75 years. * Patients scheduled for unilateral biportal endoscopic (UBE) surgery for lumbar degenerative disease at the First Affiliated Hospital of Kunming Medical University between February 2026 and December 2027. * Follow-up duration \> 6 months. * Complete clinical and follow-up data available. * Voluntary participation and signed informed consent. Exclusion Criteria: * History of tuberculosis, infection, tumor, or trauma. * Severe cardiac, hepatic, or renal insufficiency. * History of chronic lung disease, liver disease, HIV infection, diabetes, or renal insufficiency. * Psychiatric disorders or inability to comply with follow-up. * Severe osteoporosis. * Pregnant or lactating women.
Where it's running
-
The First Affiliated Hospital of Kunming Medical University
Kunming, Yunnan, China Recruiting
Study contacts
- Study coordinator: Fan Zhang, MD
- Email: zhangfan4@kmmu.edu.cn
- Phone: +86 15087160418
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Using regional anesthesia to reduce opioid use in spine surgery
This study is testing if a special pain management technique can help people having spine surgery use less opioid medication after their operation.
-
Predicting success of epidural injections for sciatica treatment
This study is trying to find out which factors can help predict how well epidural injections will work for people with sciatica caused by a herniated disc or spinal stenosis.
-
Impact of muscle degeneration on chronic low back pain after surgery
This study looks at how muscle loss affects ongoing back pain in people who have surgery for spine problems, to help improve recovery and predict results.
-
Prone lumbar disc surgery: how breathing and brain oxygen relate
This study will observe whether changes in breathing mechanics during prone lumbar disc surgery relate to brain oxygen levels in adults.
-
Acute Effects of Neurodynamics on Hamstrings in Athletes
This study tests whether neurodynamic techniques can help athletes keep or improve hamstring strength and endurance.
-
High-Intensity Laser Therapy vs Epidural Injection for Chronic Lumbar Disc Herniation Pain
This trial tests whether high-intensity laser therapy can relieve chronic low back and leg pain as well as a transforaminal epidural steroid injection in adults with lumbar disc herniation.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.