Prevalence of PAD in Patients With Surgically Treated Lumbar Spinal Stenosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study aims to determine how often peripheral artery disease coexists with lumbar spinal stenosis in adults undergoing surgical evaluation or treatment. Participants will undergo a contrast-enhanced CT scan of the lower limb arteries and a set of routine vascular tests (Doppler ultrasound, treadmill tests, and pulse-pressure measurements) to compare their diagnostic accuracy for PAD in this population. The study also includes specialized stress TcPO2 tests and an injected lower-limb aorta scan to better characterize vascular status. By identifying the prevalence and the most accurate diagnostic approach, findings could improve preoperative assessment and postoperative outcomes for patients with LSS and suspected PAD.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Presenting with a lumbar spinal stenosis with surgical indication, either unoperated or operated on less than 3 months ago
* Affiliated with a social security scheme
* Having received oral and written information about the protocol and having signed a written consent form to participate in this research.

Exclusion Criteria:

* emergency surgical care
* Contraindication to contrast enhanced CT scan

  * Stroke or myocardial infarction (MI) within the last 3 months
  * Known severe or poorly tolerated arrhythmia
  * Known severe or symptomatic left ventricular outflow obstruction
  * Decompensated heart failure
  * History within the last 3 months of venous thromboembolic disease, myopericarditis, endocarditis, aortic dissection or intracardiac thrombus
  * Severe uncontrolled hypertension (BP \> 200/110 mmHg)
  * Inability to walk on the treadmill
  * Major lower limb amputation
  * Adult subject to legal protection

Where it's running

• CHU Rennes
  Rennes, France Recruiting
• Groupement des Hôpitaux de l'Institut Catholique de Lille
  Lille, France Not yet recruiting
• Groupe hospitalier Paris Saint Joseph
  Paris, France Not yet recruiting

Study contacts

• Study coordinator: Marie-Laure Gervais
• Email: marie-laure.gervais@chu-rennes.fr
• Phone: +33299284321

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.