Evaluating a non-invasive method for cardiac resynchronization therapy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on patients with heart failure and left bundle branch block (LBBB) who are undergoing cardiac resynchronization therapy (CRT). It aims to assess the acute effects of CRT using a non-invasive device during implantation and follow-up visits. Additionally, echocardiography will be utilized to visualize changes in heart function when CRT is activated and deactivated. The goal is to improve understanding of CRT effectiveness and identify patients who may not benefit from the therapy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients referred for CRT implantation or postoperative control at Oslo University Hospital based on the European Society of Cardiology (ESC) guidelines (2021), and criteria below:

  1. Sinus rhythm.
  2. New York Heart Association class II / III heart failure on diagnosis and on optimal medical therapy.
  3. Left bundle branch block.
  4. QRS duration ≥ 130 ms.
  5. Left ventricular ejection fraction ≤ 40%.
  6. Patients must have echocardiography examination before implantation
  7. Informed consent obtained from the patient.

Exclusion Criteria:

1. Age \< 18 years and \> 80 years;
2. Ongoing atrial fibrillation;
3. Complete atrioventricular block

Where it's running

• Oslo University Hospital
  Oslo, Norway Recruiting

Study contacts

• Principal investigator: Marit Witso, MD — Oslo University Hospital
• Study coordinator: Espen W. Remme, Dr.ing
• Email: espen.remme@medisin.uio.no
• Phone: 004723071413

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.