Sponsor or institution
Clinical trials and research at University of Texas Hlth Sci Ctr Houston
As of November 12, 2026, Find a Trial lists 734 NIH-funded research projects at this institution, with $436.4 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 734NIH research projects
NIH-funded research (newest 40 of 734)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Administrative and Engagement Core to support Cancer Control efforts
This grant funds a team that helps coordinate, communicate, and engage with communities to advance cancer control efforts.
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Administrative and Engagement Core for Cancer Control
A core team will coordinate administration, communications, and community engagement to support cancer control efforts across several Texas institutions.
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Understanding how neural crest cells shape the bones of the skull
A researcher will study how signals control the skull’s sutures, with potential to improve diagnosis and treatment of conditions like craniosynostosis.
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Alzheimer’s disease and related brain changes linked to chemicals in the body
This NIH grant supports a patient-centered effort to map how environmental exposures and body chemistry relate to Alzheimer’s disease and related dementias.
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Understanding how everyday exposures affect Alzheimer's disease progression
A national research effort is studying how environmental exposures, gut health, diet, and metabolism relate to Alzheimer's and related dementias to identify new ways to diagnose and treat these conditions.
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How environment, gut health, and metabolism affect Alzheimer’s disease
This grant looks at how environmental exposures, gut microbes, diet, and metabolism influence Alzheimer’s disease and related dementias.
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Lipids and brain aging in Alzheimer's disease
Aims to understand how lipids in the body relate to aging of the brain and Alzheimer's disease by studying blood and brain-related lipid patterns.
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Metabolic clues from lipids in aging and Alzheimer's disease
A lipid-focused research effort is exploring how fat-related molecules influence brain aging and Alzheimer's disease to uncover new ideas for care.
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Understanding how chemical exposures affect Alzheimer's disease progression
This project studies how environmental chemicals and other biological factors influence brain health and the course of Alzheimer’s disease and related dementias.
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HOPE-M: How eviction moratoria affected mental health after eviction threats
This study looks at how the threat of eviction, and the end of moratorium protections, affects people's mental health in Texas.
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Metabolic changes in cells that repair blood vessels in the eye lens to prevent scarring
A drug or approach that changes how certain cells that repair blood vessels in the eye work, to prevent scarring behind the retina in age-related macular degeneration patients treated with anti-VEGF therapy.
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Mitochondrial energy problems in men and women with Alzheimer’s disease
This grant tests how mitochondria differ between men and women with Alzheimer's disease to find ways to tailor care.
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Mitochondrial energy problems in people with Alzheimer’s and related brain diseases
A research effort is looking at how mitochondrial energy problems differ between men and women with Alzheimer’s disease and related dementias and what this means for future care.
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Ethical digital twin tools to monitor complex medical devices
A patient-focused project to improve safety of medical devices by using smart, privacy-conscious AI that learns from many data sources to spot problems after devices are on the market.
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Metabolic clues from lipids to understand aging and Alzheimer’s disease
This grant studies how lipids in the body relate to aging of the brain and the risk and progression of Alzheimer’s disease and related dementias.
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TWIST1 and its regulatory pathway in craniofacial bone development
A study in humans and animals looks at how TWIST1 and IRF6 control skull and facial bone formation, which could point to new ways to prevent birth defects like cleft lip/palate.
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Improving HIV Prevention and Substance Use Care after Sexual Assault for Adolescents and Young Adults
A pilot study aims to make HIV prevention and substance use support more available for teens and young adults who have experienced sexual violence.
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LISTOS for Cancer Control: Using implementation science to spread proven cancer care
A center-led effort to speed up the use of proven cancer prevention and screening strategies in diverse health systems, especially in underserved communities.
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LISTOS for Cancer Control: Faster, Better Cancer Care Through Smarter Implementation
A national center will help health systems adopt and sustain proven cancer control programs to improve breast and colorectal cancer screening and diagnostics, especially in underserved communities.
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Intercellular communication in the retina: helping cells talk with tiny RNA messengers
Aims to understand how small RNA messages pass between retinal support cells and immune-like cells to reduce inflammation and eye injury, using engineered cell-derived vesicles.
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How brain support cells (astrocytes) affect noticing and responding to new people
This research tests whether changes in brain support cells called astrocytes change how people with autism notice and respond to new social situations.
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Nuclear receptors that may stop muscle wasting in cancer
This grant explores whether activating specific muscle-regulating receptors can prevent muscle loss in cancer patients.
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Treating Alcohol Use Disorder in Primary Care with Semaglutide
This grant tests whether the diabetes drug semaglutide can help adults reduce or stop drinking when used in primary care.
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RPE cell signaling linked to choroid damage in macular degeneration
This work looks at whether overactive signaling in retinal pigment cells causes loss of the blood-vessel layer under the retina in people with age-related macular degeneration.
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Understanding symptom burdens in people living with HIV to improve care
This grant explores how time with HIV and various symptoms relate to health outcomes, aiming to make symptom management more effective for people living with HIV.
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Understanding symptom burdens in people with HIV and diabetes/high blood pressure
Researchers will use topic modeling to find common groups of symptoms in people living with HIV, with and without diabetes and hypertension, to see how these symptom groups relate to health outcomes.
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DeepHIV-AoU: A smart approach to predicting and preventing HIV with All of Us data
A new AI-powered tool will use health data from many people to improve HIV prevention by predicting who is at higher risk and which interventions might work best.
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Cognitive screening after an aneurysmal brain bleed
Using patient questionnaires to find thinking and memory problems in people recovering from aneurysmal subarachnoid hemorrhage.
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Understanding how sensing sounds and sights affect PTSD
A study by the University of Texas Health Houston explores how abnormal brain sensing and fear networks contribute to PTSD and how these insights could guide future treatments.
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Blood test to predict delayed brain injury after an aneurysm bleed
This project is creating a blood test to spot which people who had a brain aneurysm bleed are likely to develop delayed brain injury in the days after the bleed.
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CD19-directed CAR-NK cells for systemic autoimmune diseases
A new off-the-shelf immune cell therapy using engineered NK cells to help people with systemic sclerosis and lupus who have not responded to standard treatments.
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Psilocybin-Assisted ACT for Co-Occurring Cocaine Use Disorder and Major Depressive Disorder
A new treatment combines psilocybin with Acceptance and Commitment Therapy to help people who have both cocaine use disorder and major depressive disorder.
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How brain immune cells control nerve activity in TDP‑43 dementia
Researchers are looking at whether brain immune cells called microglia can calm overactive neurons in dementias tied to TDP‑43 to help protect thinking and memory.
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Complement signaling in Alzheimer's disease: neuron and brain cell roles in memory loss
A short, patient-friendly look at how a tiny part of the immune system in the brain may contribute to memory problems in Alzheimer's disease.
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Maternal Genetic Variants and Birth Defects
This project looks at how a mother’s genetic differences may contribute to birth defects in babies.
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Drosophila model to understand how lipoprotein receptors control Alzheimer’s disease mechanisms
A study in fruit flies aims to uncover how lipid receptors like LRP1 and LDLR control processes linked to Alzheimer’s disease, which could reveal new paths for treatment or prevention for people with AD risk factors.
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Hearing aid use to lower dementia risk in older adults
Starting hearing aids in older adults may help lower the chance of developing Alzheimer’s disease and related dementias.
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Neonatal Fc receptor blockade by efgartigimod to help inflammatory nerve disease
Aims to test how blocking a specific antibody trafficking receptor with efgartigimod could improve nerve inflammation in a model of AIDP/GBS-type neuropathy.
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A regional hub to advance aging biology research in Houston
A career-focused NIH grant aims to grow aging biology research in Houston by building collaborations, training, and shared resources.
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New-onset Depression After Surgery in Older Adults
A large study will look at why some older adults develop depression after surgery, and what helps or hurts their recovery.
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