NIH-funded research R01 grant

Understanding symptom burdens in people living with HIV to improve care

Official title: Discovery of Symptom Burdens and Their Associations with Health Outcomes among People Living with HIV

Funded at University of Texas Hlth Sci Ctr Houston · NIH-11471035 · Data updated 2026-11-12

This grant explores how time with HIV and various symptoms relate to health outcomes, aiming to make symptom management more effective for people living with HIV.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas Hlth Sci Ctr Houston
NIH-funded
Lab location1 site (Houston, United States)
Project startSeptember 25, 2026
Project endJune 30, 2030
Funding year2026
Award (this year)$402,355
NIH project number1R01NR022435-01
Project IDNIH-11471035 on NIH RePORTER

Who could benefit from this research

Could help

People living with HIV who have electronic health records available for analysis and who may be candidates for symptom management strategies.

Less likely to help

Patients not engaged in care or lacking accessible health records may not directly benefit from these findings.

What this research studies

Researchers will analyze electronic health records to identify common clusters of symptoms in people with HIV and see how these clusters relate to outcomes like quality of life and mortality. The goal is to uncover patterns that could guide targeted symptom management and improve clinical care. The work will involve developing new methods and tools to detect co-occurring symptoms efficiently in real-world data. By understanding how symptom burden relates to health outcomes, clinicians can intervene earlier to prevent worsening health.

Why it matters

Potential benefit: If successful, patients with HIV could receive more timely and precise symptom management, potentially improving quality of life and survival.

How similar studies have gone: Previous work has shown that symptom patterns in chronic diseases can predict outcomes, suggesting this approach could yield actionable insights in HIV care.

Where this research is happening

  • University of Texas Hlth Sci Ctr Houston
    Houston, United States
    Active

Researchers

  • Principal investigator: Cao, Tru Hoang — University of Texas Hlth Sci Ctr Houston
  • Study coordinator: Cao, Tru Hoang

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.