Sponsor or institution

Clinical trials and research at University of North Texas Hlth Sci Ctr

• 95NIH research projects

NIH-funded research (newest 40 of 95)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• AIM-AHEAD Coordinating Center supports four core areas

  This NIH grant funds a coordinating center to advance a multi-core effort that could benefit patients through streamlined research collaboration and data sharing.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11606498

• The WNK1/OSR1 protein pathway's role in brain insulin use and age-related memory loss

  This project will see if the WNK1/OSR1 protein pathway makes the aging brain use insulin and sugar less well and whether fixing that can help memory in Alzheimer’s-related conditions.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11479058

• HBV prevention in community pharmacies: a first step in a low-resource setting

  This pilot project tests whether hepatitis B screening and vaccination can be integrated into everyday community pharmacy services to reach more people.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11473743

• Glutaredoxin and aging: how it affects cataracts and new treatment ideas

  A research project explores how aging affects the lens of the eye and tests new ways to prevent or treat cataracts by studying antioxidant repair and inflammation.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11449438

• Voltage-dependent potassium channels and tiny blood vessels in people

  This NIH grant explores how special potassium channels control tiny blood vessels in adults, which could affect blood pressure and heart health.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11437702

• Texas Center for Health Disparities: Building Leaders in Health Equity

  Aims to grow and train more health disparities researchers at UNTHSC so they can better serve communities affected by AIDS, cancers, and cardiovascular diseases.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11417334

• HABS-HD Project 3: How Environment and Culture Shape Alzheimer’s Biomarkers

  A Johns Hopkins-like project (HABS-HD Project 3) aims to understand how where people live and their social lives influence Alzheimer’s biomarkers and brain aging in order to improve prevention and care.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11412509

• HABS-HD Project 2: Understanding AD/ADRD in Diverse Adults

  This NIH grant supports a study that looks at early pathways in Alzheimer’s and related dementias to understand why black and Hispanic adults may develop symptoms differently and sooner.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11412508

• HABS-HD Project 1: Understanding Alzheimer’s Biomarkers in Diverse Communities

  A large study is looking at Alzheimer’s biomarkers in adults 21 and older across diverse communities to help improve future treatments.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11412505

• HABS-HD: Core G Development Core supports training for Alzheimer's and related dementia disparities

  A research training program focused on educating and mentoring students and early-career researchers to study Alzheimer’s and related dementias in African American and Hispanic communities.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11412503

• Biostatistics Support for Alzheimer’s Disease Research at UT Southwestern

  A biostatistics core will manage data quality and statistical analysis for a large Alzheimer’s study program to ensure reliable results.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11412500

• Disparities & Outreach Core for Alzheimer’s Research in Diverse Populations

  A national Alzheimer’s initiative is funding a core team to connect with Black, Hispanic, and White communities to understand why dementia rises in diverse groups and to help recruit more people from these communities into aging research.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11412499

• Omics Core for Alzheimer’s biomarkers across diverse populations

  A large NIH grant is funding a core that analyzes blood and CSF to find biomarkers for Alzheimer’s disease across African American, Mexican American, and White adults.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11412497

• Clinical Core for Health Disparities Alzheimer’s study

  A large, community-focused study program is continuing to gather interviews, imaging, and other assessments from adults over 50 to better understand Alzheimer’s disease in African American, Mexican American, and White populations.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11412496

• HABS-HD Core B: Brain Imaging and Data Platform for Alzheimer’s disease research

  A large NIH program provides standardized brain MRI and PET imaging data, processing, and storage to support Alzheimer’s disease research through hundreds to thousands of scans.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11412493

• HABS-HD Core A: Administration and leadership for aging brain studies

  A national study on aging brains led from a central administrative core to guide researchers in understanding biomarkers across diverse populations affected by Alzheimer’s disease and related dementias.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11412490

• Health and Aging Brain Study for Diverse Populations

  A large study is exploring how Alzheimer’s biomarkers relate to aging in Black and other diverse adults to improve understanding and future treatments.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11412481

• Lung-targeted gene delivery using tiny delivery particles

  A new gene-delivery approach uses special nanoparticles to reach and treat lung tissue through the bloodstream, potentially helping people with conditions like AAT deficiency.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11381647

• Metabolic targets to protect vision in glaucoma

  This grant explores how metabolic changes in the eye and visual pathways contribute to glaucoma and how metabolic interventions might help preserve vision.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11365427

• New inflammation pathway in diabetic kidney disease

  This project explores how inflammation in the kidney of people with diabetes may be reduced by targeting a key cell that produces inflammatory signals.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11361566

• Peptoid barcodes to track gene-delivery nanoparticles in living systems

  A new, easy-to-use barcode tool uses deuterated peptoids to label gene-carrying nanoparticles so scientists can quickly see where they go in living bodies.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11333856

• How sex and a blood‑pressure hormone in the memory center relate to Alzheimer's risk

  This work looks at whether biological sex and levels of angiotensin II in the hippocampus change Alzheimer's risk, especially in post‑menopausal women.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11308322

• AIM-AHEAD Coordinating Center for health initiatives

  This study is all about bringing together different health programs to make sure you get better access to the care you need and more effective treatments, so you can feel your best!

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11302065

• High-frequency, low-amplitude vibration device to speed healing of diabetic foot ulcers

  A handheld vibration device is being used to help people with diabetes heal stage 2 foot ulcers faster and feel better sooner.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11291877

• Using the protein PIP to help heal corneal scarring

  This project uses a naturally occurring protein called PIP to try to reduce scarring and help the cornea heal in people with corneal injuries or disease.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11285218

• How hormones and the pituitary may affect keratoconus

  This project looks at whether sex hormones and pituitary signals change the cornea in people with keratoconus to help explain why the disease starts and progresses.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11262874

• How lifestyle changes affect blood proteins that coat injected nanoparticles

  This project looks at whether stress-related lifestyle differences change which blood proteins stick to injected nanoparticles and where those particles travel in the body.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11260148

• How diabetes damages the cornea

  This research looks at whether boosting a protein called PPARα (for example with the drug fenofibrate) can protect the cornea and its nerves in adults with diabetes.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11259566

• Eye drops that protect vision in glaucoma

  This project tests special eye drops that turn into a natural estrogen inside the retina to protect nerve cells and help people with glaucoma keep their sight.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11259508

• Developing models to understand infectious diseases.

  This study is all about building models to better understand infectious diseases, so we can find better ways to treat and prevent them, ultimately helping patients like you.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11197670

• Creating an HIV-1 that can infect monkeys

  This project makes a version of HIV-1 that can infect monkeys to help researchers learn more about AIDS and speed development of vaccines and treatments.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11174578

• Understanding Alzheimer's Risk in Diverse Communities

  This research looks at how changes in our DNA might affect when Alzheimer's disease starts and how it progresses in Mexican Americans and non-Hispanic whites.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11174255

• How neighborhood, stress, and culture link to Alzheimer’s in African American and Mexican American communities

  This project looks at how neighborhood disadvantage, stress, acculturation, and experiences like racism relate to Alzheimer’s brain changes in African American and Mexican American older adults.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11173859

• Understanding Alzheimer's in African American and Mexican American adults

  This project looks at brain changes and health factors linked to Alzheimer's in African American and Mexican American adults to understand why the disease affects them differently.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11173852

• Health & Aging Brain — Alzheimer's biomarkers in African American and Hispanic adults

  This project will look at Alzheimer's-related brain changes and biomarkers across adulthood in African American and Hispanic communities to help make biomarker-based diagnosis and treatment more relevant for diverse people.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11173846

• Community outreach to include Black and Hispanic older adults in Alzheimer’s research

  This program connects older Black, Mexican American, and White adults in the Dallas–Fort Worth area with Alzheimer’s testing and enrollment so researchers can better understand differences in brain aging and dementia risk.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11173829

• Omics testing of blood and spinal fluid to find Alzheimer’s biomarkers in diverse communities

  This project uses blood and spinal fluid from African American, Mexican American, and non‑Hispanic White people to find biological signs that could help detect and track Alzheimer’s disease.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11173824

• Health & Aging Brain Clinical Center for Alzheimer's and Memory Health

  Collecting exams, brain scans, and health information from adults of different racial and ethnic groups to improve prevention and care for Alzheimer's disease.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11173819

• HABS‑HD leadership and coordination for Alzheimer’s biomarker research

  This team runs and coordinates a multi-part program that studies Alzheimer’s biomarkers in adults from diverse backgrounds to help improve future care.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11173808

• Health and Aging Brain — focusing on Alzheimer's in diverse communities

  This project compares brain scans, blood tests, and other measures in older African American and Hispanic adults to better understand Alzheimer's disease.

  NIH research University of North Texas Hlth Sci Ctr · Fort Worth, United States · NIH-11173807

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