Omics Core for Alzheimer’s biomarkers across diverse populations
Official title: HABS-HD - Core D - Omics Core
Funded at University of North Texas Hlth Sci Ctr · NIH-11412497 · Data updated 2026-11-12
A large NIH grant is funding a core that analyzes blood and CSF to find biomarkers for Alzheimer’s disease across African American, Mexican American, and White adults.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of North Texas Hlth Sci Ctr NIH-funded |
| Lab location | 1 site (Fort Worth, United States) |
| Project start | September 30, 2022 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $8,262,441 |
| NIH project number | 5U19AG078109-05 |
| Project ID | NIH-11412497 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals of African American, Mexican American, or non-Hispanic White background who may have or be at risk for Alzheimer’s disease and related cognitive impairment.
✕Less likely to help
People without Alzheimer’s disease or related cognitive concerns may not directly benefit from this core’s findings.
What this research studies
This core will collect, process, and analyze biological samples to identify omics-based biomarkers linked to Alzheimer’s disease in diverse populations. It aims to understand how biomarker profiles differ by race/ethnicity and how these profiles relate to diagnosed MCI and dementia. The work supports multi-level analyses integrating AT(N) biomarkers with omics data to inform more tailored clinical trials and treatments. Results could help improve diagnosis, prognosis, and therapeutic decisions for people at risk or living with Alzheimer’s disease.
Why it matters
Potential benefit: If successful, it could lead to more accurate, population-specific biomarkers that guide earlier diagnosis and personalized treatment plans for Alzheimer’s disease.
How similar studies have gone: Previous omics-driven biomarker research has shown promise in detecting AD-related changes, with ongoing work expanding across diverse populations.
Where this research is happening
-
University of North Texas Hlth Sci Ctr
Fort Worth, United States Active
Researchers
- Principal investigator: Johnson, Leigh a — University of North Texas Hlth Sci Ctr
- Study coordinator: Johnson, Leigh a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.