NIH-funded research NIH-funded research

Health & Aging Brain Clinical Center for Alzheimer's and Memory Health

Official title: HABS-HD - Core C - Clinical Core

Funded at University of North Texas Hlth Sci Ctr · NIH-11173819 · Data updated 2026-11-12

Collecting exams, brain scans, and health information from adults of different racial and ethnic groups to improve prevention and care for Alzheimer's disease.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of North Texas Hlth Sci Ctr
NIH-funded
Lab location1 site (Fort Worth, United States)
Project startSeptember 30, 2022
Project endAugust 31, 2027
Funding year2025
Award (this year)$15,438,376
NIH project number5U19AG078109-04
Project IDNIH-11173819 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are community-dwelling adults aged 50+ in the existing cohort or adults aged 30–49 being enrolled, especially individuals who identify as African American, Mexican American, or non-Hispanic white and who can attend Fort Worth or partner site visits.

Less likely to help

People under 30, those with neurological conditions unrelated to Alzheimer's disease, or those seeking immediate therapeutic effects are unlikely to receive direct personal health benefits from participation.

What this research studies

I would complete interviews, memory and thinking tests, medical exams, brain imaging, and may give blood or other samples as part of regular visits. The study follows people every 24 months and currently includes 3,000 adults aged 50 and older, with plans to enroll 1,500 more adults aged 30–49 across African American, Mexican American, and non-Hispanic white groups. The Clinical Core reviews data to assign research diagnoses and provides feedback to participants, families, and health care providers as part of a community 'give back' approach. Participation helps build a detailed picture of biomarkers and risk across adulthood in diverse communities.

Why it matters

Potential benefit: Could lead to more tailored prevention, diagnosis, and treatment strategies for Alzheimer's disease in diverse racial and ethnic groups.

How similar studies have gone: Large programs like the Alzheimer's Disease Neuroimaging Initiative have advanced biomarker knowledge, but population-specific work focused on African American and Mexican American groups is newer and still emerging.

Where this research is happening

  • University of North Texas Hlth Sci Ctr
    Fort Worth, United States
    Active

Researchers

  • Principal investigator: O'bryant, Sid E — University of North Texas Hlth Sci Ctr
  • Study coordinator: O'bryant, Sid E

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.