Clinical Core for Health Disparities Alzheimer’s study
Official title: HABS-HD - Core C - Clinical Core
Funded at University of North Texas Hlth Sci Ctr · NIH-11412496 · Data updated 2026-11-12
A large, community-focused study program is continuing to gather interviews, imaging, and other assessments from adults over 50 to better understand Alzheimer’s disease in African American, Mexican American, and White populations.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of North Texas Hlth Sci Ctr NIH-funded |
| Lab location | 1 site (Fort Worth, United States) |
| Project start | September 30, 2022 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $17,506,577 |
| NIH project number | 5U19AG078109-05 |
| Project ID | NIH-11412496 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults 50+ from African American, Mexican American, and non-Hispanic White communities, plus adults 30–49 for biomarker studies.
✕Less likely to help
Individuals without the ability to participate in long-term follow-up or imaging may see limited direct benefits.
What this research studies
The Clinical Core will oversee direct participant interactions and data collection for the Health & Aging Brain Study – Health Disparities, including interviews, cognitive and medical assessments, and imaging. It plans to enroll 1,500 more adults aged 30–49 and follow participants with 24-month data to examine biomarkers across adulthood. Data reviewed here will help assign research diagnoses and provide feedback to participants and their families. The study emphasizes returning information and care insights to the community as part of informed consent. Overall, this work aims to support precision approaches to prevention and treatment tailored to diverse populations.
Why it matters
Potential benefit: If successful, the project could improve understanding of Alzheimer’s disease across diverse groups and inform tailored prevention and care.
How similar studies have gone: Previous large-scale studies in diverse populations have shown that multiethnic data improves understanding of Alzheimer’s risk and progression.
Where this research is happening
-
University of North Texas Hlth Sci Ctr
Fort Worth, United States Active
Researchers
- Principal investigator: O'bryant, Sid E — University of North Texas Hlth Sci Ctr
- Study coordinator: O'bryant, Sid E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.